Quadruple therapy with moxifloxacin and bismuth for first-line treatment of Helicobacter pylori

doi:10.3748/wjg.v18.i32.4386

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Aug 28, 2012 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Aug 28, 2012; 18(32): 4386-4390
Published online Aug 28, 2012. doi: 10.3748/wjg.v18.i32.4386

Table 1 Summary of study data

Triple therapy regimen (PAM)	Quadruple therapy regimen (PAMB)
Pantoprazole 20 mg bid (8.00 am-8.00 pm)	Pantoprazole 20 mg bid (8.00 am-8.00 pm)
Amoxicillin 1 g bid (8.00 am-8.00 pm)	Amoxicillin 1 g bid (8.00 am-8.00 pm)
Moxifloxacin 400 mg bid (8.00 am-8.00 pm)	Moxifloxacin 400 mg bid (8.00 am-8.00 pm)
	Bismuth subcitrate 240 mg bid (11.00 am-11.00 pm)
Number of patients: 57	Number of patients: 50
Female/male: 30/27	Female/male: 28/22
Age: mean 49 yr, range 23-75 yr	Age: mean 50 yr, range 20-72 yr
Follow-up loss: 1	Follow-up loss: 1
UBT negative: 44	UBT negative: 46
UBT positive: 12	UBT positive: 3
Per protocol: 44/56 (78.5%)	Per protocol: 46/49 (93.8%)^a
Intention to treat: 44/57 (77.1%)	Intention to treat: 46/50 (92%)^a

^aP < 0.05 vs pantoprazole, amoxicillin and moxifloxacin (PAM). PAMB: Pantoprazole, amoxicillin, moxifloxacin and bismuth subcitrate; UBT: Urea breath test.

Citation: Ciccaglione AF, Cellini L, Grossi L, Marzio L. Quadruple therapy with moxifloxacin and bismuth for first-line treatment of Helicobacter pylori. World J Gastroenterol 2012; 18(32): 4386-4390
URL: https://www.wjgnet.com/1007-9327/full/v18/i32/4386.htm
DOI: https://dx.doi.org/10.3748/wjg.v18.i32.4386