Guidelines For Clinical Practice
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Aug 14, 2012; 18(30): 3945-3954
Published online Aug 14, 2012. doi: 10.3748/wjg.v18.i30.3945
Table 1 Overview of noninvasive methods in diagnosis of liver disease severity that have been evaluated in the context of non-alcoholic
Routine laboratory tests
Liver enzymes
Parameters of liver dysfunction
Imaging methods
Computed tomography
Magnetic resonance imaging
Magnetic resonance elastography
Liver stiffness measurement
Transient elastography (FibroScan)
Acoustic radiation force impulse shear wave imaging
Biomarkers of necroinflammation
Cytokeratin 18 fragments
High-sensitivity C-reactive protein
C-C chemokine ligand 2
Plasma pentraxin 3
Oxidative stress measurement
Tumor necrosis factor-α
Insulin resistance measurement
Multicomponent tests for diagnosis of non-alcoholic steatohepatitis
Nash test
Non-alcoholic steatohepatitis clinical scoring system for morbid obesity
Model by Miele et al[61]
Biomarkers of fibrosis
Hyaluronic acid
Type VI collagen 7S domain
Multicomponent panels for diagnosis of fibrosis
Non-alcoholic fatty liver disease fibrosis score
European liver fibrosis panel/enhanced liver fibrosis panel