Brief Article
Copyright ©2012 Baishideng Publishing Group Co.
World J Gastroenterol. Apr 7, 2012; 18(13): 1508-1516
Published online Apr 7, 2012. doi: 10.3748/wjg.v18.i13.1508
Table 1 The basic characteristics of the study population and the association of nonalcoholic fatty liver disease with gender difference
MenTotal n (%)Obese n (%)Non-obese n (%)
Number581114414370
NAFLD1874 (32.2)970 (67.3)904 (20.7%)
5 criteria of the metabolic syndrome
Increased abdominal circumference791 (13.6)703 (48.8)88 (2)
Elevated fasting glucose level1967 (33.8)704 (48.9)1263 (28.9)
Elevated blood pressure1294 (22.3)575 (39.9)719 (16.5)
Decreased HDL cholesterol level1736 (29.9)654 (45.4)1082 (24.8)
Elevated triglyceride level1063 (18.3)484 (33.6)579 (13.2)
ALT > 301269 (21.8)670 (46.5)599 (13.7)
MS defined by rNCEP-ATP III873 (15)578 (40.1)295 (6.8)
MS defined by IDF479 (8.2)443 (30.7)36 (0.8)
At least 1 criterion3680 (63.3)1291 (89.6)2389 (54.7)
At least 2 criteria1955 (33.6)957 (66.4)998 (22.8)
At least 1 criterion or ALT > 30 IU/L3885 (66.9)1337 (92.8)2548 (58.3)
Women
Number59035635340
NAFLD514 (8.7)258 (45.8)256 (4.8)
5 criteria of the metabolic syndrome
Increased abdominal circumference878 (14.9)430 (76.4)448 (8.4)
Elevated fasting glucose level679 (11.5)176 (31.3)503 (9.4)
Elevated blood pressure578 (9.8)185 (32.9)393 (7.4)
Decreased HDL cholesterol level1320 (22.4)265 (47.1)1055 (19.8)
Elevated triglyceride level195 (3.3)73 (13)122 (2.3)
Elevated ALT (ALT > 30 IU/L)200 (3.4)78 (13.9)122 (2.3)
MS defined by rNCEP-ATP III300 (5.1)174 (30.9)126 (2.4)
MS defined by IDF254 (4.3)162 (28.8)92 (1.7)
At least 1 criterion2374 (40.2)511 (90.8)1863 (34.9)
At least 2 criteria853 (14.5)355 (63.1)498 (9.3)
At least 1 criterion or elevated ALT2430 (41.2)515 (91.5)1915 (35.9)
Table 2 The role of the criteria of the metabolic syndrome in detecting or diagnosing nonalcoholic fatty liver disease in obese or non-obese population
MenWomen
Sensitivity 5 criteria of the metabolic syndromeTotal %Obese %Non-obese %P valueTotal %Obese %Non-obese %P value
Increased abdominal circumference31.4055.305.80< 0.00162.1087.6036.30< 0.001
Elevated fasting glucose level49.1052.1045.900.00836.8042.2031.300.013
Elevated blood pressure34.7044.1024.60< 0.00131.9041.5022.30< 0.001
Decreased HDL cholesterol level44.1049.1038.80< 0.00150.4056.6044.100.006
Elevated triglyceride level35.2041.0028.90< 0.00117.9020.5015.200.15
Elevated ALT (ALT > 30 IU/L)47.9059.2035.80< 0.00117.7024.0011.30< 0.001
MS defined by rNCEP-ATP III33.2048.6016.80< 0.00132.5045.0019.90< 0.001
MS defined by IDF21.0038.102.70< 0.00129.6043.4015.60< 0.001
At least 1 criterion84.8092.3076.80< 0.00186.6096.1077.00< 0.001
At least 2 criteria61.0074.2046.90< 0.00161.1077.5044.50< 0.001
At least 1 criterion or elevated ALT90.4096.2084.20< 0.00187.4096.9079.70< 0.001
Specificity
5 criteria of the metabolic syndrome
Increased abdominal circumference94.8064.5099.00< 0.00189.6033.1093.00< 0.001
Elevated fasting glucose level73.4057.7075.50< 0.00190.9078.0091.70< 0.001
Elevated blood pressure83.6068.8085.70< 0.00192.3074.4093.40< 0.001
Decreased HDL cholesterol level76.9062.2078.90< 0.00180.3061.0081.50< 0.001
Elevated triglyceride level89.7081.7090.80< 0.00198.1093.4098.40< 0.001
Elevated ALT (ALT > 30 IU/L)90.6079.6092.10< 0.00198.0094.8098.20< 0.001
MS defined by rNCEP-ATP III93.6077.3095.90< 0.00197.5081.0098.50< 0.001
MS defined by IDF97.8084.5099.70< 0.00198.1083.6099.00< 0.001
At least 1 criterion46.9015.9051.10< 0.00164.2013.8067.20< 0.001
At least 2 criteria79.4049.7083.40< 0.00190.0049.2092.40< 0.001
At least 1 criterion or elevated ALT44.3014.2048.40< 0.00163.2013.1065.40< 0.001