Age-dependent eradication of Helicobacter pylori in Japanese patients

Table 1 Demographic and clinical characteristics of patients undergoing eradication therapy for an Helicobacter pylori infection

	n = 253
Sex
Male	174
Female	79
Generation (s)
20	10
30	15
40	50
50	92
60	54
70	27
> 80	5
Diagnosis
Ulcer	165
Non-ulcer	88
Side effect
No	212
Yes	41

Ulcer: A peptic ulcer was detected by gastroscopy; Non-ulcer: No peptic ulcer was detected by gastroscopy (instead, for example, atrophic gastritis, among others); Side effects: Diarrhea (n = 23), gustatory dysfunction (n = 10), among others.

Table 2 A multivariate analysis of all patients (n = 253)

Variable	Multivariate OR	95% CI	P-value
Sex (male vs female)	1.29	0.62-2.71	0.50
Age (under 50 yr vs over 50 yr)	0.41	0.20-0.84	0.015a
Disease (ulcer vs non-ulcer)	1.61	0.79-3.30	0.19
Side effect (no vs yes)	1.59	0.67-3.80	0.29

^aStatistically significant. OR: Odds ratio; CI: Confidence interval.

Table 3 Multivariate analysis of under 50-yr-old patients (n = 75)

Variable	Multivariate OR	95% CI	P-value
Sex (male vs female)	1.46	0.49-4.33	0.50
Disease (ulcer vs non-ulcer)	0.79	0.24-2.57	0.70
Side effect (no vs yes)	3.97	1.12-14.16	0.033a

^aStatistically significant. OR: Odds ratio; CI: Confidence interval.