Update on autoimmune hepatitis

Table 1 Simplified criteria for the diagnosis of AIH by Hennes et al[35] (2008)

Criteria	1 point	2 points
IgG	> 16 g/L	> 18 g/L
ANAs, SMAs	> 1:40	> 1:80
SLA autoantibodies		Positive
Histology typical for AIH		Positive
Viral hepatitis markers		Negative
6 points: AIH very likely
8 points: AIH confirmed

Patients with IgG > 16 g/L, ANA and SMA > 1:40, and a compatible histology are assigned one point for each applicable criteria. Patients with IgG > 18 g/L, ANA and SMA > 1:80, presence of SLA/LP antibodies, histology compatible/typical for AIH, and negative viral markers are assigned two points per applicable criterion. Six or more points made the diagnosis of AIH very likely, and seven or eight points confirmed the diagnosis of definite AIH.