Copyright
©2009 The WJG Press and Baishideng.
World J Gastroenterol. Nov 28, 2009; 15(44): 5558-5562
Published online Nov 28, 2009. doi: 10.3748/wjg.15.5558
Published online Nov 28, 2009. doi: 10.3748/wjg.15.5558
Table 1 Characteristics of cirrhotic patients with SBP and cirrhotic control patients with ascites (mean ± SD)
| Control cirrhotic patients (n = 83) | Cirrhotic patients with SBP (n = 23) | |
| Age (yr) | 55.8 ± 10.5 | 58.7 ± 8.6 |
| Male gender (%) | 75.9 | 78.3 |
| Albumin (g/dL) | 3.0 ± 0.6 | 3.0 ± 0.6 |
| Prothrombin activity (%) | 63.8 ± 22.1 | 54.9 ± 20.8 |
| Bilirubin (mg/dL) | 4.9 ± 6.3 | 4.9 ± 5.9 |
| Chronic alcohol abuse as etiology of cirrhosis (%) | 71.1 | 91.3 |
Table 2 Frequencies of -2518 MCP-1 genotypes n (%)
| -2518 MCP-1 genotype | Cirrhotic patients with ascites (n = 106) | Patients with alcoholic cirrhosis and ascites (n = 80) | Heavy drinkers w/o cirrhosis (n = 118) |
| A/A | 45 (42.5) | 32 (40.0) | 64 (54.2) |
| A/G | 51 (48.1) | 39 (48.8) | 47 (39.8) |
| G/G | 10 (9.4) | 9 (11.3) | 7 (5.9) |
Table 3 Frequencies of carriers of the G-allele of the -2518 MCP-1 promoter polymorphism in patients with SBP and cirrhotic control patients with ascites n (%)
| -2518 MCP-1 genotype | Whole cohort (n = 106) | Alcoholic cirrhosis (n = 80) | ||
| No SBP (n = 83) | SBP (n = 23) | No SBP (n = 59) | SBP (n = 21) | |
| A/G or G/G | 52 (62.7) | 9 (39.1) | 40 (67.8) | 8 (38.1) |
| A/A | 31 (37.3) | 14 (60.9) | 19 (32.2) | 13 (61.9) |
-
Citation: Gäbele E, Mühlbauer M, Paulo H, Johann M, Meltzer C, Leidl F, Wodarz N, Wiest R, Schölmerich J, Hellerbrand C. Analysis of
monocyte chemotactic protein-1 gene polymorphism in patients with spontaneous bacterial peritonitis. World J Gastroenterol 2009; 15(44): 5558-5562 - URL: https://www.wjgnet.com/1007-9327/full/v15/i44/5558.htm
- DOI: https://dx.doi.org/10.3748/wjg.15.5558