Review
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. Jun 14, 2009; 15(22): 2701-2707
Published online Jun 14, 2009. doi: 10.3748/wjg.15.2701
Table 1 Endocrine disorders in relationship with H pylori infection
Endocrine disorders
Autoimmune thyroid diseases
Autoimmune atrophic thyroiditis
Hashimoto’s thyroiditis
Thyroid mucosal associated lymphocyte tissue (MALT) lymphoma
Diabetes mellitus
Dyslipidemia
Obesity
Osteoporosis
Primary hyperparathyroidism
Table 2 Endocrine disorders and eradication of H pylori
Endocrine disordersH pylori eradication
Autoimmune thyroid diseases↓ of thyroid auto-antibodies[64]
↓ of thyrotropin in H pylori+ve patients treated with T4[69]
Diabetes mellitus↓ in diabetics more than in non-diabetics[203032]
↓ in type I diabetic patients on standard triple therapy more than non-insulin dependent diabetic subjects, regardless of the dosage and/or the duration of therapy[203132]
Dyslipidemia↑ of HDL-c, apo-AI and apo-AII levels in patients with duodenal ulcers, after 1 year[86]
↑ of HDL-c and ↓ LDL-c levels in healthy subjects[78]
↓ of total cholesterol and LDL-c after 6 mo in H pylori+ve controls and H pylori+ve patients with stroke[70]
↔ of lipids in patients submitted for endoscopy[84]
↑ of total cholesterol and triglycerides in patients with peptic ulcer disease[4647] or without[87]
Obesity↑ of BMI in patients with peptic ulcer disease[4647]
↑ of the appetite of asymptomatic patients, due to ↑ of plasma ghrelin[48] and ↓ of leptin levels[4950]
↔ of plasma ghrelin levels in subjects referred for upper gastrointestinal endoscopy[4457]