Brief Articles
Copyright ©2009 The WJG Press and Baishideng.
World J Gastroenterol. May 14, 2009; 15(18): 2245-2251
Published online May 14, 2009. doi: 10.3748/wjg.15.2245
Table 1 Enrollment design
Inclusion criteriaPresence of one to three focal HCC Presence of intra-vascular1 portal vein thrombosis Child-Pugh class A or B
Patients initially enrolledMen: 190 Women: 66
Excluded for US evidence direct HCC portal vein invasion70
Drop out on follow-up78 (42%)
Liver could not be adequately visualized9
Patients studiedMean age: 66 ± 6 Men: 82 Women: 26
Table 2 Principal clinical/ultrasound features of patients
Clinical dataResults
Child A/B44/64
HCV related58
HBV related23
Alcohol related12
Mixed etiology15
Number of HCC nodules
Single nodule10
Median size44 mm (range 40-75 mm)
Two nodules22
Median size41 mm (range 33-68 mm)
Three nodules76
Median size39 mm (range 32-67 mm)
Topography of portal vein thrombosis
In right or left but not in the main portal vein80 (74%)
In main, right and left portal vein14 (13%)
In right or left and main portal vein12 (11%)
In main portal vein2 (1.8%)
Complete or incomplete vessel occlusion of on power-color-Doppler
A complete occlusion of the portal vessel99 (91%)
Incomplete thrombosis lumen9 (9%)
Table 3 Contingent tables
Patients studied on follow-up108
Malignant thrombosis58 (53.7%)
Benign thrombosis50 (46.3%)
Presence of neoplastic cells on PVT FNB1
True positive52 (48.1%)
False positive0
Not neoplastic cells on baseline PVT FNB
False negative62 (5%)
True negative50 (46.3%)
Iso-hyper-enhancement pattern1 on CEUS and mosaic pattern
True positive58
Precocious isoenhancement pattern21
Precocious hyperenhancement pattern31
Mosaic pattern36
False positive0
Hypoenhancement patternc on CEUS
False negative0
True negative50 (46.3%)