H pylori: Treatment for the patient only or the whole family?

Table 1 Relationship of family members to patients

		Group 1	Group 2	P value
	Sex	n (%)	n (%)
Spouse	Male	31 (51.7)	31 (51.7)	0.922
	Female	29 (48.3)	30 (49.2)
1. Child	Male	20 (42.6)	26 (45.6)	0.872
	Female	27 (57.5)	33 (54.4)
2. Child	Male	18 (66.7)	13 (50.0)	0.292
	Female	9 (33.3)	13 (50.0)
Mother	Female	16 (59.3)	18 (60.0)	0.991
Father	Male	11 (40.8)	12 (40.0)
Siblings	Male	3 (50.0)	3 (42.9)	0.991
	Female	3 (50.0)	4 (57.2)
Grandchild	Male	3 (60.0)	3 (42.9)	0.991
	Female	5 (40.0)	4 (57.1)

¹Fisher’s absolute χ²;

²Yates corrected χ².

Table 2 Pre-treatment H pylori positivity rates in relatives of both groups

	Group 1			Group 2		P
		n (%)			n (%)	value
Spouse	Positive	46 (76.7)		Positive	48 (78.7)	0.821
	Negative	14 (23.3)		Negative	13 (21.3)
	Total	60 (100)		Total	61 (100)
1. Child
	Positive	23 (48.9)		Positive	28 (47.5)	0.991
	Negative	24 (51.1)		Negative	31 (52.5)
	Total	47 (100)		Total	59 (100)
2. Child
	Positive	12 (44.4)		Positive	11 (42.3)	0.991
	Negative	15 (55.6)		Negative	15 (57.7)
	Total	27 (100)		Total	26 (100)
Mother
	Positive	12 (75.0)		Positive	14 (77.8)
	Negative	4 (25.0)		Negative	4 (22.2)
	Total	16 (100)		Total	18 (100)
Father
	Positive	8 (72.7)		Positive	9 (75.0)	0.991
	Negative	3 (27.3)		Negative	3 (25.0)
	Total	11 (100)		Total	12 (100)
Grandchild	Positive	2 (25.0)		Positive	2 (28.6)	0.991
	Negative	6 (75.0)		Negative	5 (71.4)
	Total	8 (100)		Total	7 (100)
Siblings	Positive	3 (50.0)		Positive	4 (57.1)	0.991
	Negative	3 (50.0)		Negative	3 (42.9)
	Total	6 (100)		Total	7 (100)

¹Fisher’s exact test.

Table 3 H pylori positivity rates after 9 mo in relatives of both groups

Group 1		Group 2
	n (%)		n (%)
Positive	5 (7.2)	Positive	27 (38.6)
Negative	65 (92.8)	Negative	43 (61.4)
Total	70 (100)	Total	70 (100)

P < 0.001, OR = 8.61, 95% CI: 2.91-22.84.