Basic Research
Copyright ©2008 The WJG Press and Baishideng.
World J Gastroenterol. Feb 28, 2008; 14(8): 1204-1211
Published online Feb 28, 2008. doi: 10.3748/wjg.14.1204
Table 1 Chromosome aberrations detected by SKY in LST-R1 cell line
64-66,XX,+der(1)t(1;3)(p11;?)t(3;19)(?;?)[21],der(2)t(2;6)(p11;q23)[30],der(2)t(2;22)(p21;?)t(3;22)(?;?)t(2;3)(?;?)[9],der(2)t(2;22)(p21;?)t(3;22)(?;?)t(2;3)(?;?)t(2;3)(q24;?)[21],-2[30],del(3)(p24)[30],-3[9],der(3)del(p12)t(2;3)(q21;q11)[21],-3[9],der(4)t(4;10)(q11;p11)[30],der(4)dup(14)(q22q31)t(4;14)(q?;q?)[9],der(4)t(3;4)(p21;p16)dup(14)(q22q31)t(4;14)(q?;q?)[21],-4[30],der(5;8)(p10;p10)[30],+i(5)(p10)×2[30],+der(5;20)(p10;q10)del(5)(q31)[30],der(6)t(2:6)(p13;q23)[30],der(7)t(7;15)(p22;q?)[30],der(7)t(7;17)(p13;?)[29],der(8)(3;8)(?;q22)[30],der(9)t(9;19)(p11;?)[30],+der(9)t(9;19)(q11;?)[30],+r(9)(p13q13)[29],der(10;13)(q10;q10)[30],der(10)t(4;10)(p11;11)t(4;8)(q31;q13)t(3;10)(p23;q23)[30],der(12)t(3:12)(q24;q11)[30],der(12)t(5;12)(?;p11)[30],+der(12)t(2;12)(q22;q11)[30],+der(12)t(2;12)(p?;p11)t(2;12)(q24;q?)[30],+der(12)t(12;20)(q24;?)[30],-13[30],-14[30],+der(15)t(6;15)(?;p11)[30],der(17)t(15:17)(q25;q24)[30],-18[30],-19[30],-19[30],-21[30],der(22)t(3;22)(?;p13)[9],-22[30][cp30]
Table 2 Genes differentially expressed in LST cells when compared with SW480 cells are functionally categorized based on the Gene Ontology terms available from the online batch extract interface for SOURCE. (http://smd.stanford.edu/cgi-bin/source/sourceBatchSearch). This table shows the genes categorized in cell adhesion
AccessionGene nameGene symbolFold change
Z24725Mitogen inducible 2MIG23.21
Z22555CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1CD36L13.10
S80990Ficolin (collagen/fibrinogen domain-containing) 1FCN12.91
AL137480Formin binding protein 4FNBP42.73
AL117505ATPase, Ca++ transporting, cardiac muscle, slow twitch 2ATP2A22.63
M26683Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)SCYA22.45
AF055084Monogenic, audiogenic seizure susceptibility 1 homolog (mouse)MASS12.39
X68264Melanoma cell adhesion moleculeMCAM2.38
AF052124Secreted phosphoprotein 1 (osteopontin, bone sialoproteinI, early T-lymphocyte activation 1)SPP12.31
M25280Selectin L (lymphocyte adhesion molecule 1)SELL2.23
M16336CD2 antigen (p50), sheep red blood cell receptorCD22.19
AL161973Myeloid/lymphoid or mixed-lineage leukemia [trithorax (Drosophila) homolog]; translocated to, 4MLLT42.14
L25286Collagen, type XV, alpha 1COL15A2.10
D83018Nel (chicken)-like 2NELL2-48.1
AB040902Fibronectin leucine rich transmembrane protein 3FLRT3-3.51
AA460440CD164 antigen, sialomucinCD164-2.23
U85611Calcium and integrin binding protein (DNA-dependent protein kinase interacting protein)CIB1-2.03
Table 3 Genes differentially expressed in LST cells when compared with LoVo cells are functionally categorized based on the Gene Ontology terms available from the online batch extract interface for SOURCE. (http://smd.stanford.edu/cgi-bin/source/sourceBatchSearch). This table shows the genes categorized in cell adhesion
AccessionGene nameGene symbolFold change
S80990Ficolin (collagen/fibrinogen domain-containing) 1FCN142.87
AL161973Myeloid/lymphoid or mixed-lineage leukemia (trithorax (Drosophila) homolog); translocated to, 4MLLT426.47
M26683Small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)SCYA224.92
M31210Endothelial differentiation, sphingolipid G-protein-coupled receptor, 1EDG111.07
Z22555CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 1CD36L14.33
M16336CD2 antigen (p50), sheep red blood cell receptorCD23.07
U43901Laminin receptor 1 (67 kD, ribosomal protein SA)LAMR12.55
M85289Heparan sulfate proteoglycan 2 (perlecan)HSPG22.11
Y13323ADAM-like, decysin 1ADAMDEC1-2.03
AL133035Filamin-binding LIM protein-1FBLP1-2.10
NM_002292Laminin, beta 2 (laminin S)LAMB2-2.10
AL161972Intercellular adhesion molecule 2ICAM2-2.12
BE301622Pinin, desmosome associated proteinPNN-2.17
AF053944AE-binding protein 1AEBP1-2.21
Y10931SymplekinSYMPK-2.24
M98457CD209 antigenCD209-2.25
D87469Cadherin, EGF LAG seven-pass G-type receptor 2, flamingo (Drosophila) homologCELSR2-2.26
AW843882Leucine-rich repeats and immunoglobulin-like domains 3LRIG3-2.26
X78947Connective tissue growth factorCTGF-2.33
AF135021Catenin (cadherin-associated protein), alpha-like 1CTNNAL1-2.36
AL136139Enhancer of filamentation 1 (cas-like docking; Crk-associated substrate related)HEF1-2.36
AF055084Monogenic, audiogenic seizure susceptibility 1 homolog (mouse)MASS1-2.37
AF039747Cadherin 10, type 2 (T2-cadherin)CDH10-2.39
U58516Milk fat globule-EGF factor 8 proteinMFGE8-2.41
D49742Hyaluronan-binding protein 2HABP2-2.42
U79716ReelinRELN-2.42
Y11307Cysteine-rich, angiogenic inducer, 61CYR61-2.45
AB007865Fibronectin leucine rich transmembrane protein 2FLRT2-2.48
NM_006149Lectin, galactoside-binding, soluble, 4 (galectin 4)LGALS4-2.52
M59807Natural killer cell transcript 4NK4-2.59
AJ009985Annexin A9ANXA9-2.61
NM_014000VinculinVCL-2.63
AL117505ATPase, Ca++ transporting, cardiac muscle, slow twitch 2ATP2A2-2.64
AF062075LeupaxinLPXN-2.67
X05610Collagen, type IV, alpha 2COL4A2-2.70
D12676CD36 antigen (collagen type I receptor, thrombospondin receptor)-like 2 (lysosomal integral membrane protein II)CD36L2-2.72
D21255Cadherin 11, type 2, OB-cadherin (osteoblast)CDH11-2.77
U70136Proteoglycan 4, (megakaryocyte stimulating factor, articular superficial zone protein)PRG4-2.77
S53911CD34 antigenCD34-2.82
AW025274Kin of IRRE like 2 (Drosophila)KIRREL2-2.85
M73255Vascular cell adhesion molecule 1VCAM1-2.86
L25286Collagen, type XV, alpha 1COL15A1-2.87
AL117604Deleted in liver cancer 1DLC1-2.91
AJ132445Claudin 14CLDN14-2.95
AL133035Filamin binding LIM protein 1FBLP1-3.14
Z24725Mitogen inducible 2MIG2-3.15
X15880Collagen, type VI, alpha 1COL6A1-3.53
AL137480Formin binding protein 4FNBP4-3.58
AF052124Secreted phosphoprotein 1 (osteopontin, bone sialoproteinI, early T-lymphocyte activation 1)SPP1-3.60
AB018269Calsyntenin 3CLSTN3-3.70
AB002298PDZ domain containing 3PDZK3-3.97
X87838Catenin (cadherin-associated protein), beta 1 (88 kDa)CTNNB1-4.64