Incidence of reflux esophagitis and Helicobacter pylori infection in diabetic patients

Table 1 Patient characteristics

	Well controlled group (%)	Poorly controlled group (%)	P
Gender (Male/Female)	(20/16)	(25/24)	0.84
Type of DM
(IDDM/NIDDM)	(1/35)	(5/43)	0.36
Age (yr)	65.9 ± 10.3	60.0 ± 11.9	0.02
Height (cm)	160.3 ± 8.7	156.9 ± 17.6	0.29
Body weight (kg)	61.4 ± 16.5	61.1 ± 17.9	0.93
BMI	23.5 ± 5.6	23.3 ± 3.1	0.77
Duration of DM (yr)	12.9 ± 10.5	16.7 ± 10.3	0.10
Hiatal hernia	33.3 (12/36)	22.4 (11/49)	0.38
Insulin therapy	33.3 (12/36)	61.2 (30/49)	0.02
Calcium antagonist	13.9 (5/36)	24.5 (12/49)	0.35
Retinopathy	16.7 (6/36)	32.7 (16/49)	0.16
Nephropathy	2.3 (1/36)	8.2 (4/49)	0.56
Neuropathy	13.9 (5/36)	20.4 (10/49)	0.45

Table 2 Comparison between diabetic patients and controls

	Diabetic patients (%)	Controls (%)	P
RE	17.6 (15/85)	10.3 (97/944)	0.056
Los angeles classification
A	80.0 (12/15)	44.3 (43/97)	0.01
B	20.0 ( 3/15)	48.5 (47/97)
C	0	6.2 (6/97)
D	0	1.0 (1/97)
Incidence of CLE	32.9 (28/85)	37.7 (356/944)	0.45

CLE: Columnar lined esophagus.

Table 3 Comparison between good and poorly glycemic controlled groups

	Well controlled group (%)	Poorly controlled group (%)	P
RE	19.4 (7/36)	16.3 (8/49)	0.93
Incidence of GERD	25.0 (9/36)	38.8 (19/49)	0.27
Symptoms	30.1 (11/36)	41.3 (20/49)	0.46
QUEST score	2.06 ± 3.16	3.37 ± 4.22	0.12
Los angeles classification
A	85.7 (6/7)	75.0 (6/8)	0.62
B	14.3 (1/7)	25.0 (2/8)
C	0	0
D	0	0
Incidence of CLE	27.8 (10/36)	36.7 (18/49)	0.52
PGI/II	4.07 ± 2.61	4.94 ± 2.31	0.19
Gastrin	166.0 ± 126.9	137.6 ± 122.8	0.40

CLE: Columnar lined esophagus.