In vitro activity of moxifloxacin and piperacillin/sulbactam against pathogens of acute cholangitis

Table 1 Patient characteristics, physical and laboratory parameters on admission

		Standard values	Scale unit
Number of patients	65	-	-
Mean age	68 ± 12.3	-	-
Gender
Male	32	-	-
Female	33	-	-
Bilirubin	7.9 ± 7.4	< 1.2	mg/dL
Alkaline phosphatase	675 ± 510	40-120	U/L
γ-Glutamyltransferase	697 ± 682	< 66	U/L
Aspartate aminotransferase	193 ± 300	10-50	U/L
Alanine aminotransferase	136 ± 147	10-50	U/L
Leucocytes	16.9 ± 10.7	4-9	G/L
C-reactive protein	17.3 ± 9.5	< 0.5	mg/dL

Table 2 Resistance pattern for moxifloxacin and piperacillin/sulbactam in all pathogens

	Moxifloxacin			Piperacillin/Sulbactam
Pathogens	Susceptible	Intermediate	Resistant	Susceptible	Intermediate	Resistant
Enterococcus species	9	4	13	16	1	9
Enterococcus NS	2	4	2	7		1
Enterococcus faecium	1		7	2	1	5
Enterococcus faecalis	4		3	5		2
Enterococcus casseliflavus	2			2
Enterococcus gallinarum			1			1
Escherichia coli	8	1	4	11		2
Klebsiella species	5	1	2	4	1	3
Klebsiella pneumoniae	3	1	2	2	1	3
Klebsiella oxytoca	2			2
Enterobacter species	5			3		2
Enterobacter cloacae	3			3
Enterobacter NS	2					2
Pseudomonas aeruginosa	2		1		1	2
Aeromonas species	1		1			2
Aeromonas hydrophila/caviae	1					1
Aeromonas NS			1			1
Citrobacter freundii	2			1	1
Coagulase neg. Staphylococcus			2			2
Gram negative rod NS	1			1
Streptococcus anginosus	1			1

NS: Not specified.