Strategy for treatment of nonerosive reflux disease in Asia

Table 1 Clinical characteristics of NERD and RE patients in Asia

	NERD	RE
Male/Female	0.59-1.65	1.18-7.13
Average age (yr)	45.2-57.5	49.0-59.7
Mean body mass index (kg/m2)	22.1-23.1	21.7-24.2
Complication of hiatal hernia (%)	17.7-34.8	35.1-77.0
H pylori infection (%)	36.3-48.3	18.0-32.3
Glandular atrophy of the gastric mucosa (open-type) (%)	25.0-43.0	6.7-25.0
Efficacy of proton pump inhibitor (%)	29.5-64.0	55.4-90.3

Table 2 Esophageal motility characteristics in NERD and RE patients in Asia

	NERD	RE
Resting LES pressure	Mildly increased	Moderately decreased
Reflux episodes/hour	Moderately increased	Moderately increased
Primary peristalsis	Normal	Moderately decreased
Secondary peristalsis	Mildly decreased	Moderately decreased
Acid clearance	Mildly delayed	Moderately delayed

LES: Lower esophageal sphincter.