Rapid Communication
Copyright ©2007 Baishideng Publishing Group Co.
World J Gastroenterol. Mar 7, 2007; 13(9): 1445-1448
Published online Mar 7, 2007. doi: 10.3748/wjg.v13.i9.1445
Table 1 Effect of KN-93 and KN-92 on cell proliferation in human hepatic stellate cells (LX-2) after 24 incubation (n = 3, mean ± SD)
Cell proliferation (% of control)
ConcentrationKN-93KN-92
Control100.00 ± 3.32100.00 ± 3.32
5 μmol/L81.76 ± 2.58a96.63 ± 2.69
10 μmol/L60.30 ± 2.59b96.24 ± 3.14
25 μmol/L33.42 ± 3.07b95.61 ± 2.81
50 μmol/L27.15 ± 2.86b96.59 ± 2.44
Table 2 Effect of 10 μmol/L KN-93 and KN-92 on cell proliferation in human hepatic stellate cells (LX-2) after treatment for various periods of time (n = 3, mean ± SD)
Cell proliferation (% of control)
Time of treatmentKN-93KN-92
Control100.00 ± 2.86100.00 ± 3.32
4 h99.56 ± 3.5397.12 ± 2.97
8 h78.27 ± 2.92b96.95 ± 2.56
16 h52.26 ± 2.90b98.34 ± 3.18
24 h30.54 ± 2.82b96.53 ± 2.67
48 h11.48 ± 3.16b97.12 ± 3.09