Higher radiation dose with a shorter treatment duration improves outcome for locally advanced carcinoma of anal canal

Table 1 Distribution of patients by the 2002 American Joint Committee on Cancer Staging Classification¹

Stage	N0	N1	N2	N3	Total
T3	6	3	6	4	19
T4	6	0	1	1	8
Total	12	3	7	5	27

¹One patient who had recurrent disease with an initial stage of T2N0 was not included in this table.

Table 2 Subgroup analysis of local control based on total radiation dose and overall treatment time

Fraction of patientscontrolled locally	High dose (> 54 Gy)	Low dose (< 54 Gy)
Short duration ( ≤ 60 d)	8/9b	4/9
Long duration (> 60 d)	2/8	1/2

^bP = 0.01 vs the rest of the subgroups.