Cytomegalovirus infection in severe ulcerative colitis patients undergoing continuous intravenous cyclosporine treatment in Japan

Table 1 Clinical and epidemiological characteristics of patients

	Male	Female	Total
Age, yr (median, range)	30 (18-56)	29 (8-56)	27 (8-56)
Gender	14	9	23
CMV infection diagnosed	11	7	18
Recent corticosteroid therapy	14	9	23
Outcome: Surgery	9	6	15
Ganciclovir therapy	2	1	3

Table 2 Utility of various tests for detection of infection with CMV in CyA treated patient with UC

Parameter	Real-time PCR(%)	Serum IgMantibodies (%)	Inclusion bodies in HEstained biopsy (%)
Number	18	16	4
Sensitivity	100	88.88	22.22
Specificity	100	100	100
PPV	100	100	100
NPV	100	71.4	26.3