Effects of H pylori infection on gap-junctional intercellular communication and proliferation of gastric epithelial cells in vitro

Table 1 Effects of intact H pylori and sonicated extracts on GJIC of SGC-7901 cells (n, mean ± SE)

Group	CagA+ strainb	CagA- strainb
Intact H pylorid	26.05 ± 3.39 (40)a	36.95 ± 3.78 (44)a
Sonicated extractsd	15.92 ± 2.53 (40)a	22.69 ± 2.60 (41)a
Negetive control	66.39 ± 9.95 (24)
Positive control (TPA)	8.47 ± 0.95 (22)

^bP < 0.01 one-way ANOVA vs negative control,

^aP < 0.05 ANOVA/Dunnett vs negative control,

^dP < 0.01 vs t-test of CagA⁺ and CagA^-H pylori strains.

Table 2 Effect of intact H pylori and sonicated extracts on proliferation of SGC-7901 cells (n, mean ± SE)

Group	CagA+ strainb	CagA- strainb
Intact H pylorid	0.755 ± 0.048 (6)a	0.680 ± 0.036 (6)a
Sonicated extractsd	0.938 ± 0.037 (6)	0.830 ± 0.056 (6)a
Negetive control	0.955 ± 0.038 (6)
Positive control (TPA)	0.986 ± 0.045 (6)

^bP < 0.01 one-way ANOVA vs negative control,

^aP < 0.05 ANOVA/Dunnett vs negative control,

^dP < 0.01 vs t-test of CagA⁺ and CagA^-H pylori strains.