Heme oxygenase-1 induction by hemin protects liver cells from ischemia/reperfusion injury in cirrhotic rats

Table 1 Gray values of caspase-3, NF-κB and HO-1 of rats (mean ± SD)

Group		n	NF-κB	Caspase-3	HO-1
Normal		6	172.0 ± 1.7	188.3 ± 3.5	158.9 ± 2.6
Liver cirrhosis		10	164.1 ± 3.5b	176.8 ± 4.9b	148.1 ± 3.7b
Sham	6 h	10	159.4 ± 4.7d	177.2 ± 2.7d	145.4 ± 2.9d
	12 h	10	159.6 ± 4.2d	178.5 ± 3.9d	146.8 ± 3.8d
I/R	6 h	10	139.7 ± 6.0	145.5 ± 14.6	125.1 ± 5.7
	12 h	9	148.1 ± 5.3	148.0 ± 6.5	132.4 ± 6.2
I/R+hemin	6 h	10	150.2 ± 8.6d	166.7 ± 8.1d	112.0 ± 8.3d
	12 h	9	151.1 ± 5.9c	172.8 ± 3.8d	120.8 ± 11.0d

^bP < 0.01 vs N group;

^cP > 0.05 vs I/R group;

^dP < 0.01 vs I/R group.