Gene expression profile analyses of mice livers injured by Leigongteng

doi:10.3748/wjg.v13.i26.3619

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 13, Issue 26

This Article

Citation of this article

Corresponding Author of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (1796)

All Articles published online

The chart showing PDF series, HTML series, Figures (1-4) series, Tables (1-2) series.

Item

Count

PDF

224

HTML

1314

Figures (1-4)

131

Tables (1-2)

127

Sum=1796

Jul 14, 2007 (publication date) through Apr 25, 2024

Times Cited of This Article

Times Cited (11)

Journal Information of This Article

Publication Name

World Journal of Gastroenterology

ISSN

1007-9327

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Rapid Communication

World J Gastroenterol. Jul 14, 2007; 13(26): 3619-3624
Published online Jul 14, 2007. doi: 10.3748/wjg.v13.i26.3619

Table 1 Physiological and biochemical indices (mean ± SD, n = 12)

	Liver index	Spleen index	ALT (U/L)	AST (U/L)	AKP (U/L)	TP (g/L)
Control group	4.31 ± 0.14	0.27 ± 0.01	35.35 ± 4.22	39.29 ± 4.33	295.31 ± 43.84	1.42 ± 0.10
Leigongteng group	5.30 ± 0.20^b	0.33 ± 0.04^b	48.71 ± 11.57^b	48.25 ± 12.27^a	367.42 ± 32.84^b	1.09 ± 0.08^b

liver index: 100 × weight of live/weight of body, spleen index: 100 × weight of spleen/weight of body.

^aP < 0.05,

^bP < 0.01.

Table 2 Differentially expressed genes of liver tissue in the Leigongteng group

Catalog	GenBank access number	Names of the genes	Cy5/Cy3(average)
Metabolism	AB059565	aldo-keto reductase family 1, member C18 (Akr1c18)	0.226
	NM_032541	hepcidin antimicrobial peptide(Hamp)	0.354
	L38990	glucokinase (Gck)	0.412
	AY273812	3-ketoacyl-CoA thiolase B(MGC29978)	0.445
	NM_013786	hydroxysteroid (17-beta) dehydrogenase 9 (Hsd17b9)	2.277
	BC010769	apolipoprotein A-IV (Apoa4)	2.759
	BC013476	cytochrome P450, family 4, subfamily a, polypeptide 10(Cyp4a10)	2.948
	BC018263	cis-retinol/3alpha hydroxysterol short-chain dehydrogenase-like(CRAD-L)	2.988
	CA478631	metallothionein 1 (Mt1)	4.404
	BC050123	asparagine synthetase (Asns)	5.031
Immune response	AK005018	H-2 class II histocompatibility antigen, E-B beta chain precursor	0.243
	BC061489	Ia-associated invariant chain (Ii)	0.311
	NM_010738	lymphocyte antigen 6 complex,locus A (Ly6a)	2.257
	AA285471	Lymphocyte antigen Ly-6F.1 precursor	2.318
	NM_011318	serum amyloid P-component(Apcs)	2.657
	M31418	interferon activated gene 202B(Ifi202b)	2.823
	NM_009117	serum amyloid A 1 (Saa1)	3.763
	BC052495	Serum amyloid A-1 protein precursor	5.467
	BG917714	lipocalin 2 (Lcn2)	8.587
	NM_011315	serum amyloid A 3 (Saa3)	13.1
Cell skeleton	BI247008	orosomucoid 2 (Orm2)	2.132
Cell skeleton	NM_145594	fibrinogen-like protein 1 (Fgl1)	2.823
Receptors	BC054522	transferrin receptor (Tfrc)	2.817
Apoptosis	AK051011	DNA fragmentation factor alpha subunit (DNA fragmentation factor 45 kDa subunit) (DFF-45)	4.042
	U44088	pleckstrin homology-like domain, family A, member 1 (Phlda1)	0.297
	NM_011817	growth arrest and DNA-damage-inducible 45 gamma (Gadd45g)	0.214
Cancer related genes	BC050858	RasGEF domain family, member1B (Rasgef1b)	2.311
Unknow	NM_183257	RIKEN cDNA 1810073K19 gene (1810073K19Rik)	0.368
Unknow	NM_025326	RIKEN cDNA 0610011I04 gene (0610011I04Rik)	2.421

Citation: Chen Y, Zhang XM, Han FM, Du P, Xia QS. Gene expression profile analyses of mice livers injured by Leigongteng. World J Gastroenterol 2007; 13(26): 3619-3624
URL: https://www.wjgnet.com/1007-9327/full/v13/i26/3619.htm
DOI: https://dx.doi.org/10.3748/wjg.v13.i26.3619