Study of the expressions of p53 and bcl-2 genes, the telomerase activity and apoptosis in GIST patients

Table 1 The expression level of telomerase and AI in tissue NSMT and GIST

Patients	n	Negative telomerase n (%)	AI (mean ± SD)
NSMT	10	-	72.1 ± 9.3
Benign GIST	9	-	45.2 ± 7.2
Potential malignant GIST	9	2 (22.8)	30.2 ± 5.6
Malignant GIST	20	17 (85.0)	11.7 ± 5.4

Table 2 Relationship between telomerase activity, AI, expression level of p53 and bcl-2 in GIST tissues (n = 9)

Telomerase group	AI (mean ± SD)	p53 (-) rate	bcl-2 (-) rate
Negative	9.5 ± 5.7b	78.9%a	84.2%a
Positive	22.9 ± 8.4	40.0%	40.0%

^aP < 0.05,

^bP < 0.01 vs Negative group.