Copyright ©2007 Baishideng Publishing Group Co.
World J Gastroenterol. May 7, 2007; 13(17): 2397-2403
Published online May 7, 2007. doi: 10.3748/wjg.v13.i17.2397
Table 1 Controlled trials of CBT in adults with irritable bowel syndrome
AuthorsDesignSample sizeOutcome
Corney et al[62] (1991)CBT vs SMT. FU at 4 & 9 mo42CBT = SMT
Greene et al[64] (1994)CBT vs SMT. FU at 3 mo20CBT > SMT
Payne et al[65] (1995)CBT vs Self-help support group vs SMT. FU at 3 mo34CBT > Self-help > SMT
Drossman et al[68] (2003)CBT vs education, and desipramine vs placebo (parallel studies). No FU431CBT > education; desipramine: placebo
Boyce et al[61] (2003)CBT vs relaxation training vs SMT. FU at 12 mo105CBT = Relaxation training = SMT
Blanchard et al[66] (2007)Group CBT vs Self-help support group vs SMT. FU at 3 mo210CBT = Support group > SMT
Kennedy et al[63] (2006)Multicenter primary care intervention by nurses. Open label. CBT + mebeverine vs mebeverine alone.149CBT + mebeverine > Mebeverine alone at 3 & 6 mo FU
Table 2 Pediatric intervention studies for children with recurrent abdominal pain
AuthorsSampleInterventionDesign# sessionsComparison sampleOutcome for intervention group relative to comparison
Finney et al[71] (1989)16 children with RAP (age 6-13)1-5 components, tailored to each child: self- monitoring, limited reinforcement of illness behavior, relaxation training, prescribed dietary fiber, required school attendanceCase controlM = 2.5 visits plus 1-6 phone calls16 untreated children with RAP matched for gender (age 4-18)-improvement or resolution of pain symptoms (parent-report) -decreased school absences -decreased health care utilization1
Robins et al[72] (2005)69 children with RAP (age 6-16)CBT family including pain management, relaxation, distraction, parental encouragement of wellness behaviorRCT5Standard care (29 of the total 69)-decreased pain (child- and parent-report) -fewer school absences
Sanders et al[69] (1989)16 children with RAP (age 6-12)CBT including self-monitoring, social learning, relaxationRCT wait-list control8Wait-list control (8 of the total 16)-decreased pain (child-report and maternal observation) -more pain-free days (child-report) -fewer pain behaviors (teacher observation) -fewer behavioral problems (parent-report)
Sanders et al[73] (1994)44 children with RAP (age 7-14)CBT including contingency management and self-managementRCT6Standard care (4-6 sessions)-more pain-free days (child-report) -fewer pain behaviors (parental observation) -less pain-related interference (child- and parent-report)
Scharff & Blanchard (1996)[70] cited in Blanchard (2001)[52]10 children with RAP (age 8-13)Random assignment to social learning or stress management/relaxationcrossover4----decreased pain intensity (child-report) -decreased pain frequency (parent-report)