Unusual causes of intrahepatic cholestatic liver disease

Table 1 Causes of cholestasis[2]

Intrahepatic cholestasis	Extrahepatic biliary tract diseases
Primary biliary cirrhosis (PBC)	Choledocholithiasis
Primary sclerosing cholangitis (PSC)	Bile duct tumours (benign and malignant)
Drugs and toxins	Ampullary tumours (benign and malignant)
Sepsis	Pancreatic carcinoma
Malignancy	Mirizzi’s syndrome
Granulomatous liver disease (infections, chemicals, drugs, miscellaneous)	AIDS cholangiopathy
Intrahepatic cholestasis of pregnancy	Parasites
Hepatitis (viral and alcoholic)	PSC (primary sclerosing cholangitis) (see left)
Genetic disorders
Total parenteral nutrition associated cholestasis
Graft versus host disease
Post liver transplant cholestasis