Evaluation of p53 codon 72 polymorphism in adenocarcinomas of the colon and rectum in La Plata, Argentina

Table 1 Genotype frequencies of p53 codon 72 polymorphism in colorectal controls and tumors according to Dukes staging

	Genotype frequencies			Odds ratio	95% CI
	Arg/Arg n (%)	Arg/Pro n (%)	Pro/Pro n (%)
Controls	44 (40.3)	53 (48.6)	12 (11.1)	1 (reference)
Carcinomas	31 (58.5)	20 (37.7)	2 (3.8)	2.08a	1.06-4.05
Dukes A-B	13 (52.0)	11 (44.0)	1 (4)	1.6	0.66-3.83
Dukes C-D	18 (64.3)	9 (32.1)	1 (3.6)	2.66a	1.12-6.29

^a P<0.05.