Absence of MutY homologue mutation in patients with multiple sporadic adenomatous polyps in Korea

Table 1 Characteristics of patients

Characteristics	Patient with CRC and adenomatous polyp (n = 10)	Patient with adenomatous polyp only (n = 20)
Sex	3 males : 1 females	15 males : 5 females
Age (yr)	Mean 45.9 (range: 21 ~ 78)	Mean 51.8 (range: 44 ~ 69)
Number of adenomatous polyps	Mean 9 (range: 1 ~ 10)	Mean 7 (range: 3 ~ 100)
Family history of adenomatous polyps	0	0

CRC: colorectal cancer.

Table 2 Primer sequences of oligonucleotide primers used for PCR-SSCP analysis of MYH

Exon	Primers	Sequences (5’ to 3’)	Length (bp)
1	M1S	CAGAGCGCAGAGGCTTTGAACA	240
	M1AS	CTGAACGGAAGTTCGACCCATC
2	M2S	AATTTGGCCTCATTGTGACTGA	221
	M2AS	AATCTGCCTTTCATGGCCAATG
3	M3S	CACAGGCTGCTGTGTCCCAAGA	259
	M3AS	CCCACCCACTGTCCCTGCTCCT
4+5	M45S	AACTCCTCATCTGGGGTTGCAT	296
	M45AS	GGTCTGACCCATGACCCTTCCC
6+7	M67S	ACCACCTTCACCCTTGACCTTG	268
	M67AS	ACCCAAGACTCCTGGGTTCCTA
8	M8S	GGAACCCAGGAGTCTTGGGTGT	222
	M8AS	AAGGAGGCTGGGCACGCACAAA
9	M9S	TTTGTGCGTGCCCAGCCTGGTT	223
	M9AS	TGCTGTGAAGCAGAGCTCCAAA
10	M10S	AAAGGAGCTCTGCTTCACAGCA	227
	M10AS	CACTCCTTAGGACTTCTCACTG
11	M11S	GTAAGCCTACTGGGGAAGGGG	222
	M11AS	GCAGAATCTTACTCAGGTTAG
12	M12S	GCCCTCTTGGCTTGAGTAGGGT	278
	M12AS	TCTCTTGTTACTCATGCCACTG
13	M13S	AGGGAATCGGCAGCTGAGGCCT	226
	M13AS	AAAAGCCAACATCCTTGGCTAT
14	M14S	TATATCCACAGGCCTATTTGAA	256
	M14AS	ATATTCATGTAGAACATGTAGG
15	M15S	GACATGAAGTTAAGGGCAGAAC	212
	M15AS	TGTTCACCCAGACATTCGTTAG
16	M16S	AACTACAAGGCCTCCCTCCTTCCA	270
	M16AS	AACAACAGGATTCTCAGGGAATG