Glutamine dipeptide for parenteral nutrition in abdominal surgery: A meta-analysis of randomized controlled trials

Table 1 Characteristics of studies included in meta-analysis on glutamine dipeptide for abdominal surgery

Authors	Journals	Year	Study design	Jadad score	Reference	Operation	Patients (Gln/Con)	Gln dipeptide (g/kg)	Days of Gln dipeptide (d) admininistration
Stehle P	Lancet	1989	RCT	3	5	Elective resection of carcinoma of colon or rectum	12 (6/6)	0.28	5 (postoperative 1-5)
O’Riordain	Annals of Surgery	1994	RCT	3	6	Colorectal Resection	22 (11/11)	0.18	5 (postoperative 1-5)
Morlion BJ	Ann Surg	1998	Double-blind RCT	4	7	Major abdominal surgery	28 (13/15)	0.3	5 (postoperative 1-5)
Metes	Clinical Nutrition	2000	RCT	4	8	Major abdominal surgery	30 (15/15)	0.5	5 (postoperative 1-5)
Jiang Z	Zhong guo Yi Xue Ke Xue Yuan Xue Bao	2000	Prospective double-blind RCT	5	9	Gastrointestinal operations	120 (60/60)	0.36	6 (postoperative 1-6)
Neri	Nutrition	2001	Multiple centers prospective double-blind RCT	3	10	Major abdominal surgery	33 (16/17)	0.18	5 (postoperative 1-5)
Fan YP	Zhonghua Wai Ke Za Zhi	2005	RCT	3	11	Abdominal surgery	40 (20/20)	0.16	7 (postoperative 1-7)
Lin MT	World J Gastroenterol	2005	RCT	4	12	Abdominal surgery	48 (25/23)	0.417	6 (postoperative 1-6)
Yao GX	Clin Nutr	2005	RCT	3	13	Gastrointestinal operations	40 (20/20)	0.5	5 (preoperative 1-postoperative 3)

RCT: Randomized controlled trial; Gln/Con: Glutamine dipeptide group/controlled group.