Loss of fragile histidine triad protein expression in inflammatory bowel disease

Table 1 Clinicopathological data of patients with inflammatory bowel disease

Patient No.	Sex	Age (yr)	Disease extension
Crohn’s disease
1	M	54	Terminal ileum
2	F	20	Ileocolonic
3	M	40	Pancolitis
4	M	70	Right-sided
5	F	62	Ileocolonic
6	M	27	Terminal ileum
7	M	26	Terminal ileum
8	F	34	Ileocolonic
9	M	51	Pancolitis
10	M	41	Pancolitis
11	M	29	Right-sided
12	F	25	Left-sided
13	M	35	Terminal ileum
14	F	38	Ileocolonic
15	F	27	Terminal ileum
16	M	31	Right-sided
17	M	42	Ileocolonic
Ulcerative colitis-active
18	M	37	Ileocolonic
19	M	45	Rectosigmoid
20	M	42	Rectosigmoid
21	M	58	Rectosigmoid
22	M	28	Rectosigmoid
23	F	26	Rectosigmoid
24	M	36	Rectosigmoid
25	M	27	Rectosigmoid
26	M	32	Rectosigmoid
27	F	47	Rectosigmoid
28	M	33	Rectosigmoid
29	M	33	Rectosigmoid
30	M	36	Left-sided
31	F	44	Rectosigmoid
32	M	41	Rectosigmoid
33	M	24	Left-sided
34	F	58	Rectosigmoid
35	F	50	Rectosigmoid
36	M	64	Rectosigmoid
37	M	48	Rectosigmoid
38	M	60	Pancolitis
39	M	35	Pancolitis
40	M	30	Rectosigmoid
41	M	13	Left-sided
42	M	52	Pancolitis
43	F	38	Pancolitis
44	M	17	Pancolitis
45	F	26	Left-sided
46	M	37	Pancolitis
47	M	20	Rectosigmoid
48	M	43	Pancolitis
49	F	51	Pancolitis
50	M	32	Rectosigmoid
Ulcerative colitis-Remittent
51	M	8	Ileocolonic
52	M	18	Rectosigmoid
53	F	35	Rectosigmoid
54	F	24	Rectosigmoid
55	M	36	Rectosigmoid
56	F	35	Rectosigmoid
57	M	35	Pancolitis
58	F	41	Pancolitis
59	M	13	Rectosigmoid
60	F	44	Pancolitis
61	F	45	Pancolitis
62	M	60	Rectosigmoid
63	M	23	Rectosigmoid
64	M	56	Left-sided

Table 2 Comparison of FHIT protein immunohistochemical expression in ulcerative colitis, Crohn’s disease, and normal colon mucosa (mean ± SD)

Groups	n	Positive rate of FHITprotein expression (%)
Normal colon mucosa	10	57.05 ± 8.86
Ulcerative colitis
Active	33	22.79 ± 16.16
Remittent	14	42.14 ± 16.82
Crohn’s disease	17	36.07 ± 19.23