Editorial
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Dec 7, 2006; 12(45): 7233-7238
Published online Dec 7, 2006. doi: 10.3748/wjg.v12.i45.7233
Table 1 Different pathways of colon cancer progression and possible therapeutic targets
PathwayTargets
Cell cylcep53, pRb, p16, p21, D-type cyclins
Apoptosis and survivalBcl-2, Cox-2
Signal transductionEGF-R, Akt, AP-1, Her2/neu, NFκB
Angiogenesis, invasion, and metastasisVEGF, TSP-1, CXCR-4
ImmunityIL-6, TGF-β