Alterations of biliary biochemical constituents and cytokines in infantile hepatitis syndrome

Table 1 Comparison of serum and biliary biochemical constituents among three groups (mean ± SD, n = 21)

Group	TBIL (μmol/L)	DBIL (μmol/L)	ALT (nkat/L)	γ-GT (nkat/L)	TBA (μmol/L)
Serum
Cholestasis	188.76 ± 72.88bd	130.76 ± 48.18bd	126.80 ± 82.12b	266.20 ± 92.73bd	118.62 ± 43.58b
Hepatitis	125.91 ± 64.28	68.67 ± 36.75b	96.11 ± 53.69b	140.57 ± 70.32a	111.89 ± 51.54b
Control	124.89 ± 62.07	6.19 ± 2.55	24.23 ± 7.17	79.06 ± 35.25	14.50 ± 9.76
Biliary
Cholestasis	78.13 ± 58.86b	52.63 ± 42.43b	8.07 ± 4.21	167.00 ± 100.06b	180.05 ± 216.98b
Hepatitis	89.95 ± 59.12b	63.56 ± 53.39b	8.21 ± 4.15	278.55 ± 201.10b	266.63 ± 268.09b
Control	252.36 ± 108.81	174.08 ± 92.56	7.22 ± 3.41	783.50 ± 363.28	643.63 ± 80.67

^aP < 0.05 vs control;

^bP < 0.01 vs control;

^dP < 0.01 vs hepatitis group.

Table 2 Comparison of serum and biliary IL-6 and TNF-α among three groups (mean ± SD, n =21, ng/L)

Group	Serum IL-6	Serum TNF-α	Biliary IL-6	Biliary TNF-α
Cholestasis	63.76 ± 26.67bd	493.11 ± 137.26bd	286.92 ± 102.02bdf	1625.89 ± 563.41bdf
Hepatitis	40.81 ± 19.32b	305.30 ± 94.45b	183.64 ± 76.94bf	1068.55 ± 383.35bf
Control	11.46 ± 6.54	214.32 ± 78.40	40.11 ± 19.89	535.80 ± 168.69

^bP < 0.01 vs control group;

^dP < 0.01 vs hepatitis group;

^fP < 0.01 vs serum.