Basic Research
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Nov 21, 2006; 12(43): 6966-6972
Published online Nov 21, 2006. doi: 10.3748/wjg.v12.i43.6966
Table 1 Expression abundance of 32 genes associated with drug-induced liver diseases during liver regeneration
Gene Recovery time (h) after partial hepatectomy (PH)
Abbr.00.51246812161824303642485460667296120144168
1 Cholestasis
Ace10.800.481.290.881.390.821.141.161.000.880.931.181.031.181.031.390.560.710.780.750.560.47
Akt110.810.760.980.861.010.871.111.120.620.713.910.652.600.530.570.681.100.971.171.020.941.01
Apoe10.931.240.870.931.070.950.760.150.931.080.130.930.171.001.000.931.071.200.331.411.231.07
Bdnf10.970.461.981.431.041.042.002.080.630.582.120.521.430.451.252.501.061.322.560.390.520.50
Cyp2d610.760.331.621.001.151.351.621.141.151.240.600.570.740.810.810.661.730.651.070.660.440.50
Ephx111.521.531.320.931.000.630.410.860.760.620.972.461.122.141.742.002.822.770.541.741.621.62
Il611.871.083.253.253.033.811.320.993.251.870.910.501.282.831.872.300.870.286.060.811.520.93
Mmp912.052.162.102.071.372.812.752.131.121.581.271.835.891.001.201.151.161.219.542.220.482.03
Slc22a110.620.880.760.660.660.590.710.860.810.821.200.711.470.410.710.621.311.051.230.810.760.71
Slc22a211.231.010.500.930.870.390.380.330.380.330.080.870.691.071.071.620.180.980.380.661.151.32
2 Fatty liver
Esr111.070.623.484.924.921.171.411.312.141.081.291.231.371.742.644.291.511.481.234.596.062.30
Fabp110.871.160.810.811.000.770.661.400.870.941.290.871.120.870.930.931.071.290.501.231.000.93
Hiat110.931.431.071.071.321.901.151.141.151.330.101.000.141.411.070.931.411.200.151.321.321.32
Hsd11b114.926.132.644.922.833.811.070.992.143.501.040.870.972.831.872.460.932.770.933.735.284.92
Il511.150.671.000.760.761.261.520.862.831.520.851.321.283.033.253.481.511.701.070.931.321.32
Mthfr10.470.441.873.252.643.193.731.500.500.381.480.661.690.660.710.870.460.402.000.570.660.50
Tnf10.870.621.231.411.151.170.930.930.710.660.791.410.851.621.071.150.930.521.233.250.810.71
Trp6313.002.442.401.060.971.702.031.581.811.350.841.191.331.552.121.621.231.121.110.741.190.90
Ugt1a110.931.431.281.231.150.990.712.061.040.881.361.041.250.950.951.081.511.340.691.421.121.08
3 Liver ischemic injury
Ces210.811.081.321.321.231.441.002.811.231.420.851.622.231.741.621.523.242.771.231.871.411.52
Ces311.743.292.463.033.032.881.320.700.871.000.640.440.600.270.440.570.331.480.711.231.621.62
Creb110.931.010.930.501.000.550.661.061.230.940.910.870.910.871.411.151.140.850.931.231.071.00
Fos128.4316.118.543.074.822.073.723.502.832.633.211.772.032.761.651.691.901.711.122.440.881.00
Per113.033.494.293.913.733.090.931.610.380.711.380.441.810.440.330.470.750.791.153.484.003.48
4 Drug hepatitis
Bcl210.820.641.121.001.191.171.150.850.330.371.800.320.790.440.390.460.810.380.840.500.680.64
Cyp2d610.760.331.621.001.151.351.621.141.151.240.600.570.740.810.810.661.730.651.070.660.440.50
Egr1117.1518.5913.932.302.002.683.480.861.622.840.643.030.562.833.253.734.582.250.663.031.000.93
Esr111.070.623.484.924.921.171.411.312.141.081.291.231.371.742.644.291.511.481.234.596.062.30
Gstm111.322.171.321.521.521.260.661.611.231.421.121.231.691.411.521.521.732.101.071.621.521.32
Il511.150.671.000.760.761.261.520.862.831.520.851.321.283.033.253.481.511.701.070.931.321.32
Mthfr10.470.441.873.252.643.193.731.500.500.381.480.661.690.660.710.870.460.402.000.570.660.50
Nat211.001.891.072.301.321.091.410.993.254.021.291.071.043.482.833.252.631.701.413.481.742.46
Pten10.661.080.930.500.470.720.760.861.231.330.791.411.041.741.321.231.621.121.411.521.321.23
Ptgs210.570.902.141.231.411.171.411.310.620.660.850.121.120.470.711.150.310.691.000.440.330.47
Trp6313.002.442.401.060.971.702.031.581.811.350.841.191.331.552.121.621.231.121.110.741.190.90
5 Granulomatous disease of the liver
Cyp2d610.760.331.621.001.151.351.621.141.151.240.600.570.740.810.810.661.730.651.070.660.440.50
6 Peliosis hepatis
Erbb210.500.101.740.660.620.340.621.400.290.171.120.411.470.500.410.470.150.151.150.250.230.31
Sult1a111.622.171.411.521.411.260.760.221.001.241.121.150.491.871.321.411.621.700.711.741.621.62