Gastric Cancer
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Nov 21, 2006; 12(43): 6949-6954
Published online Nov 21, 2006. doi: 10.3748/wjg.v12.i43.6949
Table 1 Characteristics of the studied patients (n = 58)
Characteristicsn (%)
Age (yr)
Range48-68
mean ± SD58.7 ± 3.46
Median59
Mode59
Gender
Male30 (52)
Female28 (48)
Tumor location
Gastric antrum38 (66)
Gastric body10 (17)
Gastric cardia10 (17)
Anemia
Yes48 (83)
No10 (17)
Abdominal pain
Yes27 (47)
No31 (53)
Weight los
Yes34 (59)
No24 (41)
Occult blood test
Positive43 (74)
Negative25 (26)
Table 2 Differentially expressed genes detected by cDNA microarray
GeneBankDescriptionCy3:Cy52
NM_006500MCAM (melanoma adhesion molecule)10.791
NM_002545OPCML (opioid binding protein/cell adhesion molecule-like)10.561
NM_002933RNASE1 (ribonuclease, RNase A family, 1)6.81
NM_001993F3 (coagulation factor III)6.29
NM_005433YES1(v-yes-1 Yamaguchi sarcoma viral oncogene homolog 15.9161
NM_016525UBAP (ubiquitin associated protein)5.876
NM_001428ENO1 (enolase 1)5.6921
S68616SLC9A1 (Na+/H+ exchanger NHE-1 isoform)5.484
NM_003254TIMP1 (tissue inhibitor of metalloproteinase 1)5.291
NM_005903MADH5 (mothers against decapentaplegic, homolog 5)5.083
U82828ATM (ataxia telangiectasia)0.2051
NM_006343MERTK (c-mer proto-oncogene tyrosine kinase)0.19
NM_002985SCYA5 (small inducible cytokineA5)0.191
NM_005348HSPCA (heat shock 90kD protein 1, alpha)0.164
NM_003968UBE1C (ubiquitin-activating enzyme E1C)0.161
NM_004374COX6C (cytochrome c oxidase subunit VIc)0.131
NM_002990SCYA22 (small inducible cytokine subfamily A, member22)0.129
NM_005781ACK1 (activated p21cdc42Hs kinase)0.1281
NM_005139ANXA3 (annexin A3)0.124
AF053630SERPINB1(serine proteinase inhibitor, clade B, member 1)0.123
NM_012090MACF1 (microtubule-actin crosslinking factor 1)0.098
XM_042551CAMK2A (calcium/calmodulin-dependent protein kinase)0.0645
NM_000909NPY1R (neuropeptide Y receptor Y1)0.02521
NM_015230CENTD1 (centaurin, delta 1)0.024
NM_004958FRAP1 (FK506 binding protein 12-rapamycin associated protein 1)0.0205