Hepatitis B virus genotypes in chronic liver disease patients from New Delhi, India

Table 1 Demographic and clinical characteristics of patients in the three study groups

Parameters	CRB	CHB	HCCB
n	47	40	13
Male: Female	41:6	36:4	11:2
	(6.8:1)	(9:1)	(5.5:1)
Mean age (yr)	38.36 ± 4.13a	37.65 ± 9.49	47.80 ± 18.70
ALT (nKat/ L)	1333 ± 483	1200 ± 579.5	908.5 ± 363.4
AST (nKat/L)	1152 ± 620	1283.6 ± 483	971.4 ± 360
Total Bil. (μmol/ L)	0.00016 ± 0.00012	0.00147 ± 0.00218	0.0028 ± 0.00032
IgG anti-HBc	91%	94%	93%
Risk factors
Transfusions	27%	27%	24%
Tattoo	7%	5%	6%
Operation	8%	4%	6%
Intravenous drug abuse	5%	6%	3%
Unknown	53%	58%	61%
Genotype A	(8/47) 17%	(7/40) 17%	(1/13) 7.6%
Genotype Db	(38/47) 81%	(32/40) 80%	(11/13) 85%
Genotype A+D	(1/47) 2%	(1/40) 3%	(1/13) 7.6%
HBeAg +ve (%)	77%a	82%a	51%
Sustained virological response to therapy		Genotype A: (2/ 7) 28.5%
		Genotype D: (12/32) 37.5% (P = NS)

^aP < 0.05 vs HCCB;

^bP < 0.01 vs Genotype A; NS: Not significant.