Rapid Communication
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. Oct 14, 2006; 12(38): 6167-6171
Published online Oct 14, 2006. doi: 10.3748/wjg.v12.i38.6167
Table 1 Patient demographics: IBD vs controls
Patient demographicsTotal IBDn = 116Controlsn = 116P
Median age (yr) (range)46.5 (17-74)46 (19-72)
Ethnicity0.025
Caucasian93%85%
Other (AA, Asian, Hispanic, Indian, Multicultural, West Indian)7%15%
Marital status0.4
Single21%18%
Married70%64%
Divorced7%12%
Other (widow, unknown)3%6%
Abortions (n)0.008
080%65%
111%17%
> 19%18%
Disease severity1
Mild56%
Moderate31%
Severe12%
Nonresponders2%
Family history of IBD2
Yes37%
No61%
Unknown3%
Disease duration in years
Median (yr) (range)16 (1-55)
6MP use
n55
Median (yr) (range)6 (1-26)
Imuran use
n9
Median (yr) (range)3 (1-7)
Infliximab use
n12
Median (yr) (range)1 (1-2)
Table 2 Patient demographics: CD vs UC
Patient DemographicsCD64UC52P
Median age (yr) (range)47 (20-72)45 (17-74)0.94
Ethnicity0.666
Caucasian5949
Other (AA, Asian, Hispanic, Indian, Multicultural, West Indian)53
Marital status0.914
Single1410
Married4438
Divorced43
Other (widow, unknown)
Abortions (n)0.901
05142
185
> 154
Disease severity10.2
Mild3133
Moderate2513
Severe86
Family history of IBD20.14
Primary1810
Secondary104
No family history3437
Disease duration in years
Median (yr) (range)19 (1-55)14 (1-40)0.147
6MP use
n3916
Median (yr) (range)6 (1-26)6 (1-12)0.628
Imuran use
n63
Median (yr) (range)4.5 (2-7)3 (1-4)0.433
Infliximab use
n102
Median (yr) (range)1 (1-2)1 (1)0.392
Table 3 PAP results in IBD patients vs controls
Pap resultsIBD totalControlsp
Normal95110
Abnormal216
ASCUS1112
LGSIL263
HGSIL341
Total116116
Abnormals (%)18.15.20.004
Table 4 PAP results in IBD subgroups: CD vs UC
Pap resultsCDUCp
Normal5045
Abnormal147
ASCUS174
LGSIL241
HGSIL332
Total6452
Abnormals (%)22130.793
Table 5 HPV Data in IBD patients vs controls (for abnormal Pap results)1
HPV statusIBD totalCDUCControls
Positive (high risk)5502
Positive (low risk)3030
Negative4402
Unknown9542
Total211476
Table 6 Incidence of abnormal pap results in 116 IBD patients after treatment
Pap resultsNormal papn (%)Abnormal papn (%)Total(n)P
Corticosteroids49 (80)12 (20)610.747
No corticosteroids43 (83)9 (17)52
5-ASA188 (82)20 (19)1080.934
No 5-ASA14 (80)1 (20)5
Immunosuppressives2 and Anti-TNF α354 (79)14 (21)680.381
No immunosuppressives2 and no Anti-TNF α342 (86)7 (14)49