Prevalence of H pylori associated ‘high risk gastritis’ for development of gastric cancer in patients with normal endoscopic findings

doi:10.3748/wjg.v12.i34.5509

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Sep 14, 2006 (publication date) through Apr 25, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Sep 14, 2006; 12(34): 5509-5512
Published online Sep 14, 2006. doi: 10.3748/wjg.v12.i34.5509

Table 1 Age and sex distribution of H pylori positive patients without gross pathology of gastric mucosa during upper GI-endoscopy

	*Endoscopic normal gastric mucosawith H pylori* infection**
Number (n)	845
Mean age (yr)	54.8 (18-87)
Sex
Male	450/845 (53.2%)
Female	395/845 (46.8%)
Age (yr)
< 35	114/845 (13.5%)
35-44	120/845 (14.2%)
45-54	151/845 (17.9%)
55-64	199/845 (23.6%)
65-74	166/845 (19.6%)
> 75	95/845 (11.2%)

Table 2 Frequency of intestinal metaplasia (IM) in the gastric antrum and the corpus in patients without macroscopic pathology during upper GI-endoscopy

Age (yr)	Overall IM	IM only inthe antrum	IM only in thecorpus	IM in antrumand corpus
< 35	9/114 (7.9%)	1/114 (0.9%)	7/114 (6.1%)	1/114 (0.9%)
35-44	14/120 (11.7%)	2/120 (1.7%)	12/120 (10.0%)	0/120 (0.0%)
45-54	28/151 (18.5%)	7/151 (4.6%)	18/151 (11.9%)	3/151 (2.0%)
55-64	50/199 (25.1%)	7/199 (3.5%)	35/199 (17.6%)	8/199 (4.0%)
64-75	65/166 (39.2%)	6/166 (3.6%)	51/166 (30.7%)	8/166 (4.8%)
> 75	38/95 (40.0%)	6/95 (6.3%)	24/95 (25.2%)	8/95 (8.4%)
Differences between age groups	P < 0.001 (χ²-test)	P < 0.001 (χ²-test)	P < 0.001 (χ²-test)	P < 0.001 (χ²-test)

Table 3 Frequency of severe atrophy, antrum- and corpus-gastritis score in H pylori positive patients in different age-groups in patients without macroscopic pathology during upper GI-endoscopy

Age (yr)	Severe atrophy	Antrum gastritisscore	Corpus gastritisscore
< 35	0/114 (0.0%)	3.36 ± 0.90	2.49 ± 1.17
35-44	2/120 (1.7%)	3.17 ± 0.86	2.73 ± 1.02
45-54	3/151 (2.0%)	3.32 ± 1.04	2.85 ± 1.04
55-64	4/199 (2.0%)	3.38 ± 0.94	2.93 ± 1.17
64-75	9/166 (5.4%)	3.20 ± 0.92	2.98 ± 1.08
> 75	9/95 (11.2%)	3.08 ± 0.96	3.06 ± 1.15
Differences between age groups	P < 0.001 (χ²-test)	NS (ANOVA)	P < 0.001 (ANOVA)

Table 4 Comparison of gastric cancer risk index and phenotype of gastritis in 845 patients with H pylori positive gastritis

Phenotype of gastritis	Gastric cancer risk index
Phenotype of gastritis	0 point	1 point	2 points	3 points
Antrum-predominant gastritis	156	104	21	0
Pangastritis	107	178	113	36
Corpus-predominant gastritis	2	22	62	44

Citation: Leodolter A, Ebert MP, Peitz U, Wolle K, Kahl S, Vieth M, Malfertheiner P. Prevalence of H pylori associated ‘high risk gastritis’ for development of gastric cancer in patients with normal endoscopic findings. World J Gastroenterol 2006; 12(34): 5509-5512
URL: https://www.wjgnet.com/1007-9327/full/v12/i34/5509.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i34.5509