Changes of nitric oxide and endothelin, thromboxane A2 and prostaglandin in cirrhotic patients undergoing liver transplantation

doi:10.3748/wjg.v12.i25.4049

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Jul 7, 2006 (publication date) through Apr 23, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jul 7, 2006; 12(25): 4049-4051
Published online Jul 7, 2006. doi: 10.3748/wjg.v12.i25.4049

Table 1 Changes of NO₂/NO₃ and ET levels in plasma during liver transplantation (mean ± SD, n = 27)

	NO₂/NO₃ (µmol/L)	ET (ng/L)	NO/ET
T1	27.45 ± 5.70	61.21 ± 25.38	0.54 ± 0.25
T2	35.19 ± 7.72^a	74.84 ± 29.22	0.49 ± 0.25
T3	25.64 ± 5.64^c	110.61 ± 24.65^a^c	0.24 ± 0.07^a^c
T4	35.30 ± 11.23^a^e	114.00 ± 26.73^a^c	0.32 ± 0.13^a
T5	33.86 ± 8.94^c	116.92 ± 27.08^a^c	0.28 ± 0.07^a^c

^aP < 0.05 vs T1;

^cP < 0.05 vs T2;

^eP < 0.05 vs T3. T1: induction of anesthesia; T2: 60 min after operation beginning; T3: 30 min after vascular cross-clamping; T4: 30 min postreperfusion of new liver; T5: the end of operation.

Table 2 Changes of TXB₂ and 6-keto-PGF_1a levels in plasma during liver transplantation (mean±SD, n=27)

	6-keto-PGF_1a (ng/L)	TXB₂ (ng/L)	TXB₂/6-keto-PGF_1a
T1	152.94 ± 68.67	118.27 ± 63.99	0.89 ± 0.37
T2	932.71 ± 25.66^a	297.45 ± 127.13^a	0.48 ± 0.25
T3	895.83 ± 300.71^a	265.15 ± 127.34^a	0.33 ± 0.14^a
T4	620.94 ± 282.41^a^c^e	271.26 ± 140.48^a	0.49 ± 0.21^e
T5	591.12 ± 336.57^a^c^e	208.32 ± 90.98^a^c^e	0.43 ± 0.20

^aP < 0.05 vs T1;

^cP < 0.05 vs T2;

^eP < 0.05 vs T3. T1: induction of anesthesia; T2: 60 min after operation beginning; T3: 30 min after vascular cross-clamping; T4: 30 min postreperfusion of new liver; T5: the end of operation.

Citation: Hei ZQ, Huang HQ, Luo CF, Li SR, Luo GJ. Changes of nitric oxide and endothelin, thromboxane A2 and prostaglandin in cirrhotic patients undergoing liver transplantation. World J Gastroenterol 2006; 12(25): 4049-4051
URL: https://www.wjgnet.com/1007-9327/full/v12/i25/4049.htm
DOI: https://dx.doi.org/10.3748/wjg.v12.i25.4049