Ultrasonic interventional analgesia in pancreatic carcinoma with chemical destruction of celiac ganglion

Table 1 General data of 97 PC cases

Location of tumor	Diagnosis				Size of tumor (cm)	Metastasis
	Patients n	Operation	Image+ A19-9	Image		Liver	Lung	Lymph node	Colon	Spinal column
Head of pancrreas	55	46	4	5	4.1 ± 2.3	7	-	15	1	-
Neck of pancrreas	17	13	-	4	5.5 ± 3.8	2	-	3	1	-
Body of pancrreas	12	5	3	4	4.7 ± 3.1	-	-	3	-	-
Tail of pancrreas	7	7	-	-	8.6 ± 3.5	-	-	4	-	-
Whole pancreas	6	1	3	2	-	-	1	2	-	1

Table 2 VAS, plasma Sub P (ng/L) and β-Ep (nmol/L) pre- and post-operation (mean ± SD)

Operation	VAS	Sub P	β-EP
Pre-	8.0 ± 2.3	254.1 ± 96.7	3.2 ± 0.8
Post-
1 d	5.2 ± 1.8b	231.3 ± 101.3	5.1 ± 1.2f
3 d	4.6 ± 2.1b	182.4 ± 77.6c	8.8 ± 2.1f
7 d	4.3 ± 1.3b	174.5 ± 90.3c	9.2 ± 1.8f
15 d	3.7 ± 2.0b	154.7 ± 81.2c	7.6 ± 2.0f
30 d	4.1 ± 1.9b	188.2 ± 90.6c	6.7 ± 1.6f

VAS: ^aP < 0.05,

^bP < 0.01 vs Preoperation; Sub P:

^cP < 0.05, ^dP < 0.01 vs Preoperation; β-EP: ^eP < 0.05,

^fP < 0.01 vs Preoperation.

Table 3 Blood T cell subtypes (%) and β-EP (nmol/L) pre- and post-operation (mean ± SD)

Index	Control(n = 38)	Therapeutic (n = 96)
		Pre-	Postoperation
			3 d	7 d	15 d	30 d
CD3+	70.3 ± 4.9	46.7 ± 3.7	48.8 ± 5.1	58.7 ± 3.7b	62.5 ± 5.5b	61.2 ± 6.1b
CD4+	46.6 ± 5.3	31.2 ± 5.0	33.1 ± 3.8	37.6 ± 4.1d	40.6 ± 4.4d	39.6 ± 3.1d
CD8+	23.4 ± 4.1	15.0 ± 2.5	14.7 ± 2.8	20.9 ± 3.0f	22.0 ± 2.7f	21.4 ± 3.2f
β-EP	8.7 ± 2.3	3.2 ± 0.8	8.8 ± 2.1h	9.2 ± 1.8h	7.6 ± 2.0h	6.7 ± 1.6h

CD₃⁺: ^aP < 0.05,

^bP < vs Preoperation; CD₄⁺: ^cP < 0.05,

^dP < 0.01 vs Preoperation; CD₈⁺: ^eP < 0.05,

^fP < 0.01 vs Preoperation; β-EP: ^gP < 0.05,

^hP < 0.01 vs Preoperation.