Investigation of HER-2 codon 655 single nucleotide polymorphism frequency and c-ErbB-2 protein expression alterations in gastric cancer patients

Table 1 Clinicopathological details of gastric carcinoma cases

		Patients (n)
Gender	Male	15
	Female	10
Age (yr)( mean ± SD)	35-80, (58.8 ± 12.8)
Histologic type (Lauren)	Intestinal	16
	Diffuse	8
	Adenosquamous	1
Histologic type (WHO)	Well	7
	Moderatelly	5
	Poorly	4
Serosa invasion	Positive	19
	Negative	11ND
Nodal involvement	Positive	14
	Negative	61ND

¹ Not Determined: 5 cases were endoscopic biopsy samples so cannot be determined.

Table 2 Summary of HER-2 SNP presence and c-erbB-2 expression in gastric carcinoma cases

PatientNo	Classification according to Lauren	Stage	Ile/Val genotype	Immunohistochemical expression score for c-erbB-2
1	D	4	-	0
2	D	4	-	0
3	I	4	+	1
4	D		-	0
5	D		-	0
6	D	4	-	0
7	D	3	-	0
8	D	4	-	0
9	I	4	-	0
10	I	4	+	3
11	D	3	-	0
12	I	4	-	2
13	I	2	-	1
14	I	4	-	0
15	I	4	-	1
16	I	4	+	0
17	I	1	-	1
18	I	4	+	3
19	I		-	1
20	I	4	-	2
21	I	2	-	2
22	I		-	0
23	I		-	2
24	I	3	-	0
25	Other	4	-	0

D: diffuse type; I: intestinal type; (-): negative; (+): positive.