Modern management of rectal cancer: A 2006 update

Table 1 Oncologic outcome for transanal excision of rectal cancer

Study (yr)	n	Follow-up (mo)	Local recurrence (%)	Overall survival (%)
Taylor et al (1998)[45]	24	52	T1: 40 T2: 50	67
Chakravarti et al (1999)[44]	52	52	T1: 11 T2: 62	66
Steele et al (1999)[43]	1101	48	T1: 7 T2: 20	T1: 87 T2: 85
Mellgren et al (2000)[42]	108	53	T1: 17 T2: 46	69
Paty et al (2002)[10]	125	80	T1: 17 T2: 26	T1: 74 T2: 72
Endreseth et al (2005)[12]	35	24-97	T1: 12	T1: 70
Madbouly et al (2005)[11]	52	55	T1: 29	T1: 89

¹Patients with T2 cancers on pathology were treated with postoperative chemoradiation.

Table 2 Oncologic outcome for potentially curative radical rectal resection of rectal cancer according to the principles of TME

Study (yr)	n	Follow-up mo	Dukes stage n (%)	Local recurrence (%)	Overall survival (%)
Enker et al (1995)[57]	246	72	B: 99 (40) C: 147 (60)	7	LN negative: 87 LN positive: 64
Heald et al (1998)[56]	519	99	A: 102 (20) B: 167 (32) C: 142 (27) D: 108 (21)	3	80 (DFS)
Martling et al (2000)[55]	381	24	A: 128 (34) B: 140 (37) C: 112 (29) Not Documented: 1 (< 1)	6	79
Wibe et al (2002)[58]	686	29	A: 165 (24) B: 261 (38) C: 260 (38)	7	Not Reported
Nesbakken et al (2003)[59]	134	38	A: 38 (28) B: 56 (42) C: 40 (30)	9	66
Bulow et al (2003)[64]	311	36	A 73 (23) B: 143 (46) C: 93 (30) Not documented: 2 (1)	11	77

LN: Lymph node; DFS: Disease free survival.