Rapid Communication
Copyright ©2006 Baishideng Publishing Group Co.
World J Gastroenterol. May 14, 2006; 12(18): 2928-2931
Published online May 14, 2006. doi: 10.3748/wjg.v12.i18.2928
Table 1 Clinical characteristics of patients and controls
SubjectsnSex
HBV marker of mother
HBIg injection in pregnancy
MaleFemaleHBsAg+HBsAg+ and HBeAg+YesNo
Group I46262015311030
Group II73413225481647
χ20.00150.03390.0020
P0.96950.85390.9640
Table 2 Frequencies of IFN-γ+874 genotype in patients and controls
SubjectsnNumber of subjects and percentage ofIFN-γ+874 genotype (%)
AAATTT
Group I4631 (67.4)9 (19.6)6 (13.0)
Group II7333 (45.2)22 (30.1)18 (24.7)
χ25.102
P0.02389
Table 3 +874T and +874A IFN-γ allele frequencies in patients and controls
Allele(n)IFN-γ+874A/T allelefrequencies (%)
OR(95% confidence interval)χ2P
+874A+874T
3.228
Group I46 (92)71 (77.17)21 (22.83)(1.244-3.992)7.2380.0071
Group II73 (146)88 (60.27)58 (39.73)
Table 4 IFN-γCA microsatellite morphisms in patients and controls
nNumber and percentage of genotype of IFN-γCA (%)
(CA12)+/(CA12)+(CA12)+/(CA12)-(CA12)-/(CA12)-
Group I425 (11.90)11 (26.19)26 (61.91)
Group II6818 (26.47)23 (33.82)27 (39.71)
χ25.640
P0.0176
Table 5 IFN-γ CA repeat times in patients and control
IFN-γ CArepeatGroup 1Group IIχ2P
(84)
(136)
% (n)% (n)
111.19 (1)0.74 (1)0.1190.7302
1225 (21)43.38 (59)7.5480.00601
1313.10 (11)8.82 (12)1.0080.3155
1440.48 (34)33.82 (46)0.9890.3201
1513.10 (11)7.35 (10)1.9740.1600
164.76 (4)3.68 (5)0.1550.6936
172.38 (2)2.21 (3)0.0070.9327