Effects of fermented soy milk on the liver lipids under oxidative stress

Table 1 Composition of different diets (g/25 g)¹

	CC2	HCS	LCS	HCM	LCM
Corn starch	13.2	4.8	9.0	6.7	9.8
Casein	5.0	4.4	4.7	2.1	4.0
Cellulose	1.6	1.1	1.4	1.1	1.4
Soybean oil	1.5	1.5	1.5	1.5	1.5
Mineral mixture	1.5	0.9	1.2	0.9	1.2
Sucrose	1.5	0.9	1.2	0.9	1.2
Vitamin mixture	0.5	0.3	0.4	0.3	0.4
Methionine	0.1	0.1	0.1	0.1	0.1
Fermented soy milk		10.0	5.0
Milk yogurt				10.0	5.0

¹Diets were iso-caloric;

²CC, control group; HCS, high-dose fermented soy milk powder; LCS, low-dose fermented soy milk powder; HCM, high-dose fermented milk powder; LCM, low-dose fermented milk powder.

Table 2 Body weights of each group fed with different diets (mean±SD, g)

	Wk 0	Wk 2	Wk 4	Wk 6	Wk 8
	(Before injection of CCl4)			(After injection of CCl4)
CC1	223.6±13.61	267.4±16.51	317.0±30.2	371.9±36.5	402.1±25.2
HCS	237.7±11.81	276.5±11.11	338.7±14.11	395.3±17.91	429.0±27.01
LCS	231.4±14.31	272.1±11.01	329.2±9.41	395.0±17.91	435.4±26.71
HCM	231.6±9.71	264.7±9.41	314.3±11.0	367.4±12.82	403.1±10.3
LCM	225.2±10.8	260.6±14.3	309.9±19.9	364.5±17.02	405.3±17.4

¹CC, HCS, LCS, HCM, LCM, as in Table 1. n = 7-9.

Table 3 Plasma ALP concentration (IU/dL) of each group fed with different diets¹

	Wk 0	Wk 2	Wk 4	Wk 6	Wk 8
	(Before injection of CCl4)			(After injection of CCl4)
CC	33.8±0.0	51.3±9.5	43.8±14.0	194.4±65.6	303.7±119.9
HCS	50.2±11.1	70.5±8.9	57.8±6.6	472.6±235.1	338.6±130.3
LCS	49.9±21.3	64.2±4.4	47.1±3.6	278.6±205.7	360.7±206.1
HCM	35.1±6.9	56.4±4.9	39.2±6.7	577.8±74.2	548.0±150.8
LCM	37.7±6.8	57.3±8.0	43.0±3.5	255.1±170.3	592.8±115.6

Table 4 Activities of antioxidative enzymes and concentrations of TBARS, TC, and TG of the liver in CCl₄-treated rats¹ (mean±SD)

	Baseline	CC1	HCS	LCS	HCM	LCM
CAT2	0.92±0.19	0.25±0.14	0.30±0.123	0.45±0.25	0.47±0.16	0.44±0.27
GPx	703±154	615±166	680±141	857±179	734±94	762±120
GR	613±288	591±160	768±94	906.4±158	772±283	668±125
SOD	0.118±0.035	0.094±0.015	0.082±0.007	0.088±0.026	0.111±0.035	0.084±0.024
TBARS	6.32±0.71	5.53±1.00	6.08±0.77	4.79±0.67	6.24±0.97	5.92±0.97
TC	5.54±0.73	6.69±2.77	5.37±2.71	4.16±1.55	7.07±2.83	7.06±2.85
TG	12.82±0.69	15.86±3.93	18.633±5.62	16.76±0.067	19.60±0.79	20.62±5.21