Plasma leptin and ghrelin concentrations in patients with Crohn’s disease

Table 1 Plasma leptin and ghrelin levels in patients with CD and controls with or without H pylori infection (mean±SD)

	CD	Controls
		H pylori-infected	H pylori-uninfected
Body mass index (kg/m2)	20.5±0.4 (16.2-29.9)1	21.3±0.8 (16.4-28.5)	20.8±0.5 (16.4-26.7)
Plasma ghrelin levels (fmol/mL)	195.7±1.5 (45.7-368.7)	143.4±7.1 (53.2-481.0)	182.4±1.4 (75.7-322.2)
Plasma leptin levels (ng/mL)	3.8±0.4 (0.0-15.0)	4.3±0.6 (0.8-8.4)	3.8±0.6 (0.0-10.8)

¹Mean±SD (range).

Table 2 Plasma leptin and ghrelin levels in terms of various parameters (mean±SD)

	Ghrelin (fmol/mL)	Leptin (ng/mL)	Body mass index
Disease activity
Active (n = 5)	220.6±98.8	4.7±4.1	19.9±4.5
Inactive (n = 23)	202.3±86.4	3.6±2.4	20.6±2.7
Disease location
Small intestine (n = 3)	186.3±68.6	2.8±2.3	18.5±1.6
Large intestine (n = 10)	246.8±83.3	4.2±3.3	20.9±2.4
Small and large intestine (n = 15)	186.8±92.4	4.1±3.1	20.5±4.0
Anal lesion
Present (n = 7)	213.4±85.1	3.4±2.5	20.1±4.8
Absent (n = 21)	206.5±92.4	4.1±3.2	20.5±2.6
Medical treatment
5-Aminosalicylates (n = 16)	185.5±86.5	2.8±1.5	20.1±2.4
5-Aminosalicylates and elementary diet (n = 7)	229.5±98.9	4.8±3.6	20.1±5.2
No medications (n = 5)	243.4±76.8	5.7±4.8	21.8±3.1
Helicobacter pylori status
Positive (n = 5)	265.8±109.8	3.5±2.6	20.2±3.4
Negative (n = 23)	195.7±81.5	5.5±3.9	21.8±0.1