Scattered and rapid intrahepatic recurrences after radio frequency ablation for hepatocellular carcinoma

Table 1 Characteristics of the patients

	Scattered recurrence (–)	Scattered recurrence (+)	Total
n	127	11	138
Age	67.5±8.6	69.2±8.1	67.6±8.5
Sex (male/female	71/56	8月3日	79/59
Virus (HBV/HCV)	14/113	3月8日	17/121
Tumor size (mm)	24.3±13.7	20.1±5.7	24.0±13.5
Albumin (g/dL)	3.65±0.38	3.52±0.57	3.64±0.39
Bilirubin (mg/dL)	0.86±0.51	1.02±0.44	0.87±0.50
ALT (U/L)	48.4±28.3	56.0±17.8	49.0±28.5
Platelet (x104/mL)	10.9±5.5	9.0±3.6	10.7±5.5
Child–Pugh (CH1/A/B/C)a	3/102/20/2	0/5/5/1	3/107/25/3
Device and Protocolb
Original cool-tip	28	9	37
Modified cool-tip	28	0	28
Single-step LeVeen	37	2	39
Multi-step LeVeen	34	0	34
Prognosis (alive/death)b	87/40	3月8日	90/48
Observation period (mo)	27.1±11.0	24.0±11.5	26.9±11.1

^aP<0.05,

^bP<0.01 between the patients with and without scattered recurrences (χ² test).

¹CH: chronic hepatitis.

Table 2 Details of the patients with scattered recurrence

n	Sex	Age	Background	Liver function	Location/	Device	Protocol	Form of	Interval between RFA	Prognosis
				(Child-Pugh)	Size (mm)	recurrence	and recurrence (mo)	after RFA (mo)
1	F	75	LC (HCV)	C	S8/15	LeVeen	Original	Bilobular	3	Death (15)
2	M	61	LC (HBV)	A	S7/20	Cool-tip	Original	Bilobular	3	Alive (42)
3	F	79	LC (HCV)	B	S2/25	Cool-tip	Original	Bilobular	2	Death (36)
4	M	63	C (HBV)	A	S4/15	Cool-tip	Original	Surrounding	7	Death (24)
5	M	69	LC (HCV)	B	S7/26	Cool-tip	Original	Bilobular	4	Death (27)
6	M	73	LC (HCV)	B	S5/13	Cool-tip	Original	Bilobular	5	Death (20)
7	M	74	LC (HCV)	A	S4/18	Cool-tip	Original	Bilobular	4	Death (7)
8	M	70	LC (HCV)	A	S8/30	Cool-tip	Original	Surrounding	5	Alive (36)
9	M	70	LC (HCV)	B	S8/25	Cool-tip	Original	Bilobular	6	Death (16)
10	M	51	LC (HBV)	B	S6/20	LeVeen	Original	Surrounding	2	Death (10)
11	F	76	LC (HCV)	A	S3/14	Cool-tip	Original	Lobular	7	Alive (31)