He Jie Tang in the treatment of chronic hepatitis B patients

doi:10.3748/wjg.v11.i42.6638

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Nov 14, 2005 (publication date) through Apr 26, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Viral Hepatitis

World J Gastroenterol. Nov 14, 2005; 11(42): 6638-6643
Published online Nov 14, 2005. doi: 10.3748/wjg.v11.i42.6638

Table 1 Levels of ALT, AST, TB, and HBV-DNA before and after the treatment (mean±SD)

		n	ALT (U/L)	AST (U/L)	TB (μmol/L)	HBV-DNA (copy/mL)
Group III		20	21.52±8.90	15.56±7.65	11.75±5.71	<1 000
Group I	Pre-T	50	232.52±12.25	139.65±9.62	43.35±5.86	(1.62±0.81)×10^8.31
	Post-T	50	33.26±9.35^b	35.18±8.26^b	19.95±5.12^b	(9.25±1.90)×10^5.02a
Group II	Pre-T	35	225.70±11.61	135.45±9.21	41.45±5.85	(1.47±0.65)×10^8.22
Post-T		35	30.86±8.95^b	65.68±8.82^b	29.55±546^b	(8.26±2.20)×10^7.62

Pre-T: before treatment; Post-T: after treatment; ^aP＜0.05 vs before treatment in the same group;

^bP＜0.01 vs before treatment in the same group.

Table 2 T lymphocyte subsets before and after the treatment (mean±SD)

		n	CD₃ (%)	CD₄ (%)	CD₈(%)	CD₄/CD₈
Group III		20	68.10±9.25	39.27±8.70	30.96±6.82	1.70±0.72
Group I	Pre-T	50	65.55±8.22	35.06±5.38^b	34.80±4.36^b	1.10±0.35^b
	Post-T	50	67.35±8.85	37.60±8.52^a	31.95±5.61^a	1.31±0.42^a
Group II	Pre-T	35	65.86±9.21	35.15±6.01^b	35.10±6.56^b	1.07±0.46^b
	Post-T	35	66.71±9.56	35.92±8.55	34.66±6.25	1.12±0.36

Pre-T: before treatment; Post-T: after treatment;

^bP<0.01 vs group III ;

^aP＜0.05 vs before treatment in the same group.

Table 3 Serum levels of TNF-α, sIL-2R, and IL-8 as well as NK activity before and after the treatment (mean±SD)

		n	TNF-a (mg/L)	sIL-2R (kU/L)	IL-8 (μg/L)	NK (%)
Group III		20	0.58±0.23	310.0±30.7	0.72±0.2	59.65±7.5
Group I	Pre-T	50	18.8±8.9^b	390.9±12.0^b	2.42±0.8^b	43.12±6.5^b
	Post-T	50	10.5±6.8^a	310.22±8.9^a	1.12±0.5^a	52.90±7.0^a
Group II	Pre-T	35	19.0±7.2^b	395.7±16.5^b	2.45±0.8^b	43.02±6.8^b
	Post-T	35	15.62±7.9	355.6±9.5	1.80±0.7	46.54±6.9

αPre-T: before treatment; Post-T: after treatment;

^aP＜0.05 vs before treatment in the same group;

^bP<0.01 vs group III.

Table 4 T lymphocyte subsets in responders and non-responders of group I before and after the treatment (mean±SD)

		n	CD₃ (%)	CD₄ (%)	CD₈ (%)	NK (%)
Responders	Pre-T	7	66.02±8.86	35.10±4.76^b	34.92±4.36^b	43.52±7.1^b
	Post-T	7	67.80±9.11	38.85±8.85^a	30.15±5.82^a	55.60±8.2^a
Non-responders	Pre-T	43	65.50±9.08	34.92±6.30^b	34.77±6.56^b	42.93±6.7 ^b
	Post-T	43	66.09±9.35	35.99±8.70	34.25±5.52	45.60±6.5
Group III		20	68.10±9.25	39.27±8.70	30.96±6.82	59.65±7.5

^aP<0.05 vs before treatment in the same group;

^bP<0.01 vs group III.

Citation: Chen ZX, Zhang SJ, Lao SX, Hu HT, Zhang CY, Guan SH, Gu YL. He Jie Tang in the treatment of chronic hepatitis B patients. World J Gastroenterol 2005; 11(42): 6638-6643
URL: https://www.wjgnet.com/1007-9327/full/v11/i42/6638.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i42.6638