Specific ssDNA concentration in liver tissue as an index of apoptosis in hepatitis C virus-infected patients

Table 1 Correlation between ALT, AST activity, prothrombin time, and INR index in chronic hepatitis C patients

	ALT	AST	Prothrombintime	INRindex
Pearson test	0.08	0.14	-0.01	0.03

Table 2 Concentration of apoptosis ssDNA in respect to serum HCV-RNA concentration, necroinflammatory changes (G) and fibrosis (S) in liver tissue

n	G1+G2	Concentration ofssDNA (μg/g)	Concentrationof HCV-RNA(geq/mL)	Pearson test	n	S	Concentration of ssDNA (μg/g)	Concentrationof HCV-RNA (geq/mL)	Pearsontest
16	0-3	13.16×10-5	4.96-54.2×103	-0.11	39	0-1	12.71×10-5	4.96-227×103	0.01
		3.95×10-5 SD±					4.85-10-5 SD±
13	4	13.41×10-5	2.48×10-227×103	-0.14	8	2-3	16.65×10-5	14.7-266×103	0.01
		6.0×10-5 SD±;					5.98×10-5 SD±
18	5-7	13.56×10-5	14.7-266×103	-0.13
		5.85×10-5 SD±;

Necroinflammatory activity: G1 = 0-4; G2 = 0-4; G1/2 = 0-8; S = 0-4.