Best method of detecting prior Helicobacter pylori infection

Table 1 The results of Helico Blot 2.1 and various H pylori-specific antigens in 25 H pylori infected patients with a total of 112 sera samples

	HB2.11	116 ku (CagA)	89 ku (VacA)	37 ku	35 ku	30 ku (Urease A)	19.5 ku	CIM2
Positive	110/112	111/112	94/112	44/112	35/112	97/112	78/112	93/112
sera (%)	-98	-99	-84	-39	-31	-87	-70	-83

¹HB2.1: Helico Blot 2.1;

²CIM: current infection marker.

Table 2 The positive numbers and rates of various H pylori-specific antigens and Helico Blot 2.1 in 25 H pylori-infected patients at half-year intervals during a 4-year follow-up period (n, %).

Pre-Hp Tx		Post-Hp Tx
		0.5 yr	1 yr	1.5 yr	2 yr	2.5 yr	3 yr	3.5 yr	4 yr
CIM2	23 (92)	21 (95)	13 (93)	7 (78)	12 (80)	9 (75)	4 (80)	3 (50)	1 (25)
19.5 ku	23 (92)	18 (82)	7 (50)	6 (67)	8 (53)	8 (67)	4 (80)	3 (50)	1 (25)
30 ku	24 (96)	21 (95)	11 (79)	8 (89)	12 (80)	10 (83)	5 (100)	4 (67)	2 (50)
35 ku	11 (44)	9 (41)	4 (29)	3 (33)	3 (20)	4 (33)	0 (0)	1 (17)	0 (0)
37 ku	17 (68)	11 (50)	5 (36)	2 (22)	5 (33)	2 (17)	1 (20)	1 (17)	0 (0)
89 ku	22 (88)	18 (82)	13 (93)	6 (67)	13 (87)	10 (83)	4 (80)	4 (67)	4 (100)
116 ku	25 (100)	22 (100)	14 (100)	9 (100)	15 (100)	12 (100)	5 (100)	6 (100)	3 (75)
HB2.11	24 (96)	22 (100)	14 (100)	9 (100)	15 (100)	11 (92)	5 (100)	6 (100)	4 (100)
Total	25	22	14	9	15	12	5	6	4
case nos.

¹HB2.1: Helico Blot 2.1;

²CIM: current infection marker; Pre-Hp Tx: before H pylori eradication therapy; Post-Hp Tx: after H pylori eradication therapy.