Thermo-chemo-radiotherapy for advanced bile duct carcinoma

Table 1 Cases with bile duct carcinoma treated with thermo-chemo-radiotherapy

Case	Age (yr)	Sex	Unresectable reasons
1	70	m	Extensive involvement of hepatic hilus
2	57	m	Involvement of the portal vein
3	73	m	Extensive involvement of hepatic hilus
4	70	m	Involvement of the portal vein
5	70	f	Involvement of the portal vein
6	78	m	Involvement of the portal vein
7	65	m	Involvement of the portal vein
8	71	m	Extensive involvement of hepatic hilus

Table 2 Thermo-chemo-radiotherapy in each case

Case	Heat session	Chemotherapy	Dose of radiation (Gy)
1	× 4, × 4	MTX + 5Fu	50 + 40
2	× 2, × 6	CDDP + 5Fu	46
3	× 6	MTX + 5Fu	56
4	× 4	MTX + 5Fu	56
5	× 4	CDDP + 5Fu	50
6	× 2	CDDP + 5Fu	46
7	× 2	MTX + 5Fu	50
8	× 2	MTX + 5Fu	16

MTX: Methotrexate, 5Fu: 5-fluorouracil, CDDP: cis-platinum.

Table 3 Effectiveness of thermo-chemo-radiotherapy and survival months

Case	Resolution of the bile duct	Survival months
1	Complete response	33
2	Complete response	22
3	Complete response	22
4	Partial response	21.5
5	Partial response	6
6	No change	13.5
7	No change	4
8	No change	2.5