Differences in biological features of gastric dysplasia, indefinite dysplasia, reactive hyperplasia and discriminant analysis of these lesions

doi:10.3748/wjg.v11.i23.3595

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Jun 21, 2005 (publication date) through Sep 18, 2024

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World Journal of Gastroenterology

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1007-9327

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Gastroenterol. Jun 21, 2005; 11(23): 3595-3600
Published online Jun 21, 2005. doi: 10.3748/wjg.v11.i23.3595

Table 1 Expressions of PCNA in different lesions.

PCNA expression	RH	IDys	Dys	IGC
-	0	0	0	0
+	25	9	0	0
++	17	24	9	1
+++	1	2	15	11
++++	0	0	11	24
Total	43	35	35	36

Table 2 Results of discriminant analysis and its cross-validated various lesions.

Membership	Predicted group					Total
Membership	PATH	RH	IDys	Dys	IGC	Total
Original Count	RH	29 (67.4)	13 (30.2)	1 (2.3)	0 (0.0)	43
	IDys	9 (25.7)	24 (68.6)	1 (5.7)	0 (0.0)	35
	Dys	0 (0.0)	3 (8.8)	24 (70.6)	7 (20.6)	34
	IGC	0 (0.0)	1 (3.0)	4 (12.1)	28 (84.8)	33
	Ungrouped cases	1 (50.0)	1 (50.0)	0 (0.0)	0 (0.0)	2
Cross-validated Count	RH	28 (69.8)	12 (32.6)	1 (2.3)	0 (0.0)	43 (100.0)
	IDys	14 (40.0)	20 (54.3)	1 (5.7)	0 (0.0)	35 (100.0)
	Dys	0 (0.0)	4 (11.8)	24 (67.6)	7 (20.6)	35 (100.0)
	IGC	0 (0.0)	3 (3.0)	19 (15.2)	47 (81.8)	69 (100.0)

The discriminant functions are as follows: Y_RH = -11.354+4.573MUC5AC+30.432Ki-67+5.027PCNA. Y_IDys = -15.404+3.895MUC5AC+39.669Ki-67+6.032 PCNA. Y_Dys = -31.031+0.823MUC5AC+60.027Ki-67+9.605 PCNA .Y_IGC = -45.525-0.322MUC5AC+74.916Ki-67+11.542PCNA.

Citation: Dong B, Xie YQ, Chen K, Wang T, Tang W, You WC, Li JY. Differences in biological features of gastric dysplasia, indefinite dysplasia, reactive hyperplasia and discriminant analysis of these lesions. World J Gastroenterol 2005; 11(23): 3595-3600
URL: https://www.wjgnet.com/1007-9327/full/v11/i23/3595.htm
DOI: https://dx.doi.org/10.3748/wjg.v11.i23.3595