Glutamine is highly effective in preventing in vivo cobalt-induced oxidative stress in rat liver

Table 1 Effect of glutamine on antioxidant enzyme activities in cobalt-treated rat liver (mean±SD, n = 6).

Treatment	CAT(pmol/mg protein)	GSH-Px (U/mg protein)1	Total SOD (U/mg protein)
Control	2.5±0.2	0.16±0.01	7.6±0.4
CoCl2	1.7±0.1a	0.11±0.01a	5.7±0.4a
Gln	2.4±0.3	0.15±0.01	7.2±0.7
Gln + CoCl2	1.8±0.1a	0.11±0.01a	5.1±0.4a

Rats were killed 12 h after the beginning of the experiment.

¹One unit of the enzyme represents the decrease of 1mmol of NADPH/min under assay conditions.

^aP<0.05 vs control group.