Effects of 7.5% hypertonic saline on fluid balance after radical surgery for gastrointestinal carcinoma

Table 1 Diseases and surgery modes of experimental group and control group.

	Experimental group	Control group
Gastric carcinoma
Distal gastrectomy D2	8	8
Proximal gastrectomy D2	2	2
Total gastrectomy D3	2	2
Carcinoma of the colon
Sigmoid colon D3 excision	4	4
Right-half colon D3 excision	2	2
Left-half colon D3 excision	1	1
Transverse colon D3 excision	1	1
Rectal carcinoma
Dixon procedure	4	4
Miles procedure	2	2

Table 2 Comparison of general data between experimental group and control group.

	Experimental group	Control group	t or χ2	P
Sex (male/female cases)	12/14	15/11	χ2 = 0.69	0.405
Age (yr)	57.19±9.58	55.19±13.48	t = 0.567821	0.575221
Body weight (kg)1	55.58±9.44	58.21±9.72	t = 1.074640	0.292797
Serum sodium (mmol/L)1	139.9±22.46	139.31±3.87	t = 0.813147	0.423811
HCT1	0.33±0.07	0.34±0.07	t = 0.773980	0.4462
Serum albumin (g/L)1	38.35±3.53	39.42±3.73	t = 1.001330	0.326262
PaO2/FiO2 ratio1	395.88±45.55	410.43±60.33	t = 1.021750	0.316684
MAP (mmHg)2	91.88±11.31	96.17±13.35	t = 1.145300	0.263864
Heart rate (times/min)2	89.38±12.85	88.54±11.49	t = 0.223948	0.824775
POSSUM score	34.54±4.83	33.46±4.12	t = 0.951963	0.35023
Operative period (min)	252.42±73.35	248.85±73.19	t = 0.208407	0.836599
Blood transfusion (cases)	8	5	χ2 = 0.92	0.3367

¹Examination results before surgery.

²Result at time of entering SICU.

Table 3 Fluid infusion volumes (mL) of experimental group and control group.

	During surgery	Operative day	First postoperative day
Experimental	3607.69±1029.15	7140.23±1497.91	3051.58±968.16
Control	3657.69±1086.34	8888.04±1389.93	4458.85±1415.86
t	0.19256	4.95373	4.06869
P	0.848859	0.000042	0.000415

Table 4 Comparison of urine outputs (mL) between experimental group and control group.

	During surgery	Operation day	First postoperative day
Experimental	630.77±212.64	2446.73±361.12	2641.65±558.97
Control	723.08±316.93	1735.31±381.04	1998.65±482.76
t	1.08112	6.958838	4.56932
P	0.289961	<0.000001	0.000114

Table 5 Comparison of fluid balance and body weight between experimental group and control group.

	VPFB on operativeday (mL)	VPFB in 48 hafter surgery (mL)	BW increase value (kg)	BW fallingtime (h)
Experimental	2832.85±970.67	2519.15±1629.44	3.46±1.15	18.38±7.16
Control	4944.46±1289.67	6887.31±2115.84	6.96±2.41	29.58±7.80
t	7.47581	9.19234	7.09647	7.23379
P	<0.000001	<0.000001	<0.000001	<0.000001

Note: VPFF = volume of positive fluid balance; BW = body weight.

Table 6 Comparison of complications and mortality (cases) between the two groups.

	Wound infection	Pulmonary infection	Ileus	Anastomotic leak	Death
Experimental	2	0	0	0	0
Control	3	4	1	1	1
χ2	0.22	4.33	1.02	1.02	1.02
P	0.6381	0.0374	0.3126	0.3126	0.3126