Expression of platelet-derived growth factor-BB in liver tissues of patients with chronic hepatitis B

Table 1 PDGF-BB expression levels in liver samples with different stages of fibrosis

Stages of fibrosis	Case numbers	Expression levels (mean ± SD)
S0	7	4.71 ± 1.50
S1	17	6.47 ± 2.50
S2	8	11.63 ± 5.66a
S3	6	9.33 ± 2.73a
S4	5	16.50 ± 5.74a

^aP < 0.05 vs S₀.

Table 2 PDGF-BB expression levels in liver tissues with dif-ferent grades of necroinflammatory activity

Grades of inflammatory	Case numbers	Expression levels
activity		(mean ± SD)
G1	13	4.85 ± 1.57
G2	14	8.21 ± 4.17a
G3	12	10.67 ± 4.12b
G4	4	17.33 ± 6.11b

^aP < 0.05 vs G₁;

^bP < 0.01 vs G₁.

Table 3 PDGF-BB expression scores in liver tissues of differ-ent histological grading groups

Grades of histological finding	Cases numbers	Expression levels
		(mean ± SD)
Mild	27	6.59 ± 3.58
Moderate	10	10.20 ± 4.16a
Sever	6	15.60 ± 5.37b

^aP < 0.05 vs mild group;

^bP < 0.01 vs mild group.

Table 4 Relationship between PDGF-BB expression levels in liver tissues of different fibrosis stages, necroinflammatory activity and histological grades

	Coefficients as compared with
	PDGF-BB expression levels (τ)
Stages of fibrosis	0.55b
Grades of inflammatory activity	0.58b
And histological findings	0.55b

^aP < 0.05;

^bP < 0.01.

Table 5 Relationship between serum fibrosis parameters and PDGF-BB expression levels in liver tissues of different fibrosis stages

Staging of fibrosis(S)	Cases	PDGF-BB	HA (μg/L)	LN(μg/L)	PCIII(μg/L)	IV-C(μg/L)
S0	7	4.71 ± 1.50	102.67 ± 60.38	138.23 ± 17.69	137.80 ± 35.57	58.71 ± 17.40
S1	17	6.47 ± 2.50	168.74 ± 159.76	129.97 ± 30.15	143.91 ± 51.13	64.12 ± 20.26
S2	8	11.63 ± 5.66	434.86 ± 360.58	156.39 ± 39.06	163.74 ± 70.56	86.04 ± 41.94
S3	6	9.33 ± 2.73	430.60 ± 325.37	172.65 ± 39.77	192.65 ± 40.05	115.60 ± 30.62
S4	5	16.50 ± 5.74	392.30 ± 245.53	163.25 ± 26.26	154.68 ± 22.24	122.10 ± 21.34
Coefficients (r)		...	0.38a	0.33a	0.32a	0.40b

^aP < 0.05;

^bP < 0.01.