Expression and significance of VEGF-C and FLT-4 in gastric cancer

Table 1 Expression of VEGF-C and FLT-4 in primary gastric cancers and adjacent normal tissues detected by semi-quanti-tative RT-PCR (mean ± SD)

	Cases	VEGF-C	FLT-4
Primary gastric cancers	80	0.555 ± 0.399a	0.335 ± 0.261b
Adjacent normal tissues	80	0.146 ± 0.311c	0.153 ± 0.275d

^aP = 0.01 vs group^c,

^bP = 0.038 vs group^d.

Table 2 Expression of VEGF-C and FLT-4 in primary gastric cancers and adjacent normal tissues detected by immumohis-tochemistry

Positive expression	Primary gastric		Adjacent normal
	cancer (cases)		tissue (cases)
	VEGF-C	FLT-4	VEGF-C	FLT-4
+	3	2	2	3
++	7	8	4	5
+++	20	18	3	3
++++	25	21	2	3

Table 3 Correlation between pathological factors and VEGF-C expression in 80 primary gastric cancers

Pathological factors	No. of cases	VEGF-C mRNA	P
		(mean ± SD)
Histological type
Moderately-Poorly	51	0.485 ± 0.345	P = 0.032
differential
Highly differential	29	0.200 ± 0.290
Lymph node metastasis
Positive	54	0.579 ± 0.290	P = 0.024
Negative	26	0.282 ± 0.314
Serosal invasion
Positive	59	0.567 ± 0.268	P = 0.219
Negative	21	0.390 ± 0.330